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Recombinant Human DPYS, His-tagged

Cat.No. : DPYS-12157H
Product Overview : Recombinant Human DPYS protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
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Description : Dihydropyrimidinase catalyzes the conversion of 5,6-dihydrouracil to 3-ureidopropionate in pyrimidine metabolism. Dihydropyrimidinase is expressed at a high level in liver and kidney as a major 2.5-kb transcript and a minor 3.8-kb transcript. Defects in the DPYS gene are linked to dihydropyrimidinuria.
Source : E.coli
Species : Human
Tag : His
Protein length : C-term-286a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : DPYS dihydropyrimidinase [ Homo sapiens ]
Official Symbol : DPYS
Synonyms : DPYS; dihydropyrimidinase; DHPase; hydantoinase; dihydropyrimidine amidohydrolase; DHP;
Gene ID : 1807
mRNA Refseq : NM_001385
Protein Refseq : NP_001376
MIM : 613326
UniProt ID : Q14117
Chromosome Location : 8q22
Pathway : Drug metabolism - other enzymes, organism-specific biosystem; Drug metabolism - other enzymes, conserved biosystem; Fluoropyrimidine Activity, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of nucleotides, organism-specific biosystem; Pantothenate and CoA biosynthesis, organism-specific biosystem;
Function : amino acid binding; dihydropyrimidinase activity; dihydropyrimidinase activity; dihydropyrimidinase activity; metal ion binding; phosphoprotein binding; thymine binding; uracil binding; zinc ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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