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Recombinant Human DSG1 protein, His-tagged

Cat.No. : DSG1-12178H
Product Overview : Recombinant Human DSG1 protein(756-1049 aa), fused with His tag, was expressed in E.coli.
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Source : E.coli
Species : Human
Tag : His
Form : The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH7.4). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. The elution buffer contain 300mM imidazole.
Protein Length : 756-1049 aa
AA Sequence : KKLADISLGKESYPDLDPSWPPQST EPVCLPQETEPVVSGHPPISPHFGT TTVISESTYPSGPGVLHPKPILDPL GYGNVTVTESYTTSDTLKPSVHVHD NRPASNVVVTERVVGPISGADLHGM LEMPDLRDGSNVIVTERVIAPSSSL PTSLTIHHPRESSNVVVTERVIQPT SGMIGSLSMHPELANAHNVIVTERV VSGAGVTGISGTTGISGGIGSSGLV GTSMGAGSGALSGAGISGGGIGLSS LGGTASIGHMRSSSDHHFNQTIGSA SPSTARSRITKYSTVQYSK
Purity : 85%, by SDS-PAGE with Coomassie Brilliant Blue staining.
Storage : Short-term storage: Store at 2-8°C for (1-2 weeks).
Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles.
Reconstitution : Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage.
Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage.
Gene Name : DSG1 desmoglein 1 [ Homo sapiens ]
Official Symbol : DSG1
Synonyms : DSG1; desmoglein 1; DSG; desmoglein-1; CDHF4; DGI; cadherin family member 4; desmosomal glycoprotein 1; pemphigus foliaceus antigen; DG1; PPKS1; SPPK1;
Gene ID : 1828
mRNA Refseq : NM_001942
Protein Refseq : NP_001933
MIM : 125670
UniProt ID : Q02413

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How is DSG1 expression regulated in the skin? 08/06/2021

Various factors, including cytokines and growth factors, can regulate the expression of DSG1 in skin cells.

Are there any clinical trials focused on DSG1 protein therapies? 11/17/2020

Some clinical trials may be exploring DSG1-based therapies for skin disorders, but you should consult clinical trial databases for specific information.

What other medical conditions are associated with DSG1 protein? 08/15/2020

DSG1 abnormalities are primarily linked to skin disorders, but some studies suggest potential connections to oral mucosa disorders.

Can DSG1 be used as a biomarker for skin cancer? 04/14/2018

While DSG1 is not a direct biomarker for skin cancer, its expression levels may be altered in some skin cancers.

Can DSG1-targeted therapies be used to treat skin conditions? 11/30/2016

Research is ongoing, but DSG1-targeted therapies have the potential to treat conditions related to DSG1 deficiencies.

Customer Reviews (3)

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02/22/2023

    Its impeccable purity and integrity make it a valuable asset in my research endeavors.

    03/02/2022

      Their team of experts has been instrumental in resolving any queries or challenges I encountered regarding the application and utilization of the DSG1 protein.

      03/22/2021

        The DSG1 protein surpasses expectations in terms of quality and is an ideal match for my experimental requirements.

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