Recombinant Human DUSP19, GST-tagged


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Recombinant Human DUSP19, GST-tagged

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Cat.No. : DUSP19-12211H
Product Overview : Recombinant Human DUSP19 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description : Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP19 contains a variation of the consensus DUSP C-terminal catalytic domain, with the last serine residue replaced by alanine, and lacks the N-terminal CH2 domain found in the MKP (mitogen-activated protein kinase phosphatase) class of DUSPs (see MIM 600714) (summary by Patterson et al., 2009 [PubMed 19228121]).
Source : E.coli
Species : Human
Tag : GST
Protein length : 1-217a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : DUSP19 dual specificity phosphatase 19 [ Homo sapiens ]
Official Symbol : DUSP19
Synonyms : DUSP19; dual specificity phosphatase 19; dual specificity protein phosphatase 19; DUSP17; SKRP1; LMW-DSP3; protein phosphatase SKRP1; dual specificity phosphatase TS-DSP1; SAPK pathway-regulating phosphatase 1; low molecular weight dual specificity phosphatase 3; stress-activated protein kinase pathway-regulating phosphatase 1; LMWDSP3; TS-DSP1; MGC138210;
Gene ID : 142679
mRNA Refseq : NM_001142314
Protein Refseq : NP_001135786
MIM : 611437
UniProt ID : Q8WTR2
Chromosome Location : 2q32.1
Function : JUN kinase phosphatase activity; MAP-kinase scaffold activity; hydrolase activity; mitogen-activated protein kinase kinase kinase binding; protein kinase activator activity; protein kinase inhibitor activity; protein tyrosine phosphatase activity; protein
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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