Recombinant Human EDAR, GST-tagged EDAR-12275H

Recombinant Human EDAR, GST-tagged

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Recombinant Human EDAR, GST-tagged

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Cat.No. : EDAR-12275H
Product Overview : Recombinant Human EDAR protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description : This gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.
Source : E.coli
Species : Human
Tag : GST
Protein length : 207-448a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : EDAR ectodysplasin A receptor [ Homo sapiens ]
Official Symbol : EDAR
Synonyms : EDAR; ectodysplasin A receptor; DL, ectodysplasin 1, anhidrotic receptor , ED3; tumor necrosis factor receptor superfamily member EDAR; ED1R; ED5; EDA1R; EDA3; Edar; EDA-A1 receptor; downless homolog; ectodysplasin-A receptor; downless, mouse, homolog of; ectodermal dysplasia receptor; anhidrotic ectodysplasin receptor 1; ectodysplasin 1, anhidrotic receptor; DL; ED3; HRM1; EDA-A1R; FLJ94390;
Gene ID : 10913
mRNA Refseq : NM_022336
Protein Refseq : NP_071731
MIM : 604095
UniProt ID : Q9UNE0
Chromosome Location : 2q13
Pathway : Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem;
Function : protein binding; receptor activity; transmembrane signaling receptor activity;

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