Recombinant Human EIF3J, GST-tagged
Cat.No. : | EIF3J-12371H |
Product Overview : | Recombinant Human EIF3J protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | Eukaryotic initiation factor-3 (EIF3) has a molecular mass of about 600 kD and contains 13 nonidentical protein subunits, including EIF3J. EIF3 plays a central role in binding of initiator methionyl-tRNA and mRNA to the 40S ribosomal subunit to form the 40S initiation complex (Fraser et al., 2004 [PubMed 14688252]; Fraser et al., 2007 [PubMed 17588516]). |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-258a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | EIF3J eukaryotic translation initiation factor 3, subunit J [ Homo sapiens ] |
Official Symbol : | EIF3J |
Synonyms : | EIF3J; eukaryotic translation initiation factor 3, subunit J; EIF3S1, eukaryotic translation initiation factor 3, subunit 1 alpha, 35kDa; eukaryotic translation initiation factor 3 subunit J; eIF3 alpha; eIF3 p35; eIF3j; eIF-3-alpha; eukaryotic translation initiation factor 3 subunit 1; eukaryotic translation initiation factor 3, subunit 1 alpha, 35kDa; eukaryotic translation initiation factor 3, subunit 1 (alpha, 35kD); EIF3S1; eIF3-p35; eIF3-alpha; |
Gene ID : | 8669 |
mRNA Refseq : | NM_003758 |
Protein Refseq : | NP_003749 |
MIM : | 603910 |
UniProt ID : | O75822 |
Chromosome Location : | 15q21.1 |
Pathway : | Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S, organism-specific biosystem; Cap-dependent Translation Initiation, organism-specific biosystem; Eukaryotic Translation Initiation, organism-specific biosystem; Formation of a pool of free 40S subunits, organism-specific biosystem; Formation of the ternary complex, and subsequently, the 43S complex, organism-specific biosystem; GTP hydrolysis and joining of the 60S ribosomal subunit, organism-specific biosystem; Gene Expression, organism-specific biosystem; |
Function : | protein binding; contributes_to translation initiation factor activity; |
Products Types
◆ Recombinant Protein | ||
EIF3J-3189H | Recombinant Human EIF3J Protein, GST-tagged | +Inquiry |
EIF3J-1720R | Recombinant Rat EIF3J Protein, His (Fc)-Avi-tagged | +Inquiry |
EIF3J-1248R | Recombinant Rhesus Macaque EIF3J Protein, His (Fc)-Avi-tagged | +Inquiry |
EIF3J-2001C | Recombinant Chicken EIF3J | +Inquiry |
EIF3J-4733H | Recombinant Human Eukaryotic Translation Initiation Factor 3, Subunit J, His-tagged | +Inquiry |
◆ Lysates | ||
EIF3J-6657HCL | Recombinant Human EIF3J 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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