Recombinant Human EME1, GST-tagged EME1-12431H

Recombinant Human EME1, GST-tagged

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Recombinant Human EME1, GST-tagged

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Cat.No. : EME1-12431H
Product Overview : Recombinant Human EME1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description : This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in multiple transcript variants.
Source : E.coli
Species : Human
Tag : GST
Protein length : C-term-350a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : EME1 essential meiotic endonuclease 1 homolog 1 (S. pombe) [ Homo sapiens ]
Official Symbol : EME1
Synonyms : EME1; essential meiotic endonuclease 1 homolog 1 (S. pombe); crossover junction endonuclease EME1; FLJ31364; MMS4L; SLX2 structure specific endonuclease subunit homolog A (S. cerevisiae); SLX2A; hMMS4; MMS4 homolog; homolog of yeast EME1 endonuclease; essential meiotic endonuclease 1 homolog 2; SLX2 structure-specific endonuclease subunit homolog A;
Gene ID : 146956
mRNA Refseq : NM_001166131
Protein Refseq : NP_001159603
MIM : 610885
UniProt ID : Q96AY2
Chromosome Location : 17q21.33
Pathway : Fanconi anemia pathway, organism-specific biosystem; Fanconi anemia pathway, conserved biosystem; Homologous recombination, organism-specific biosystem; Homologous recombination, conserved biosystem;
Function : DNA binding; endonuclease activity; hydrolase activity; metal ion binding; protein binding;

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