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Recombinant Human EME1 Protein (1-583 aa), His-SUMO-tagged

Cat.No. : EME1-1106H
Product Overview : Recombinant Human EME1 Protein (1-583 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Cell Biology. Protein Description: Full Length of Isoform 2.
  • Specification
  • Gene Information
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Description : Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks.
Source : E. coli
Species : Human
Tag : His-SUMO
Form : Tris-based buffer, 50% glycerol
Molecular Mass : 80.8 kDa
Protein length : 1-583 aa
AA Sequence : MALKKSSPSLDSGDSDSEELPTFAF LKKEPSSTKRRQPEREEKIVVVDIS DCEASCPPAPELFSPPVPEIAETVT QTQPVRLLSSESEDEEEFIPLAQRL TCKFLTHKQLSPEDSSSPVKSVLDH QNNEGASCDWKKPFPKIPEVPLHDT PERSAADNKDLILDPCCQLPAYLST CPGQSSSLAVTKTNSDILPPQKKTK PSQKVQGRGSHGCRQQRQARQKEST LRRQERKNAALVTRMKAQRPEECLK HIIVVLDPVLLQMEGGGQLLGALQT MECRCVIEAQAVPCSVTWRRRAGPS EDREDWVEEPTVLVLLRAEAFVSMI DNGKQGSLDSTMKGKETLQGFVTDI TAKTAGKALSLVIVDQEKCFSLELL FFDFLPCTSAQNPPRRGKQGANKQT KKQQQRQPEASIGSMVSRVDAEEAL VDLQLHTEAQAQIVQSWKELADFTC AFTKAVAEAPFKKLRDETTFSFCLE SDWAGGVKVDLAGRGLALVWRRQIQ QLNRVSLEMASAVVNAYPSPQLLVQ AYQQCFSDKERQNLLADIQVRRGEG VTSTSRRIGPELSRRIYLQMTTLQP HLSLDSAD
Purity : > 90% as determined by SDS-PAGE.
Notes : Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
Storage : The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
Concentration : A hardcopy of COA with concentration instruction is sent along with the products.
Gene Name : EME1 essential meiotic endonuclease 1 homolog 1 (S. pombe) [ Homo sapiens ]
Official Symbol : EME1
Synonyms : EME1; FLJ31364; MMS4L; SLX2A; hMMS4; MMS4 homolog;
Gene ID : 146956
mRNA Refseq : NM_001166131
Protein Refseq : NP_001159603
MIM : 610885
UniProt ID : Q96AY2

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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