Recombinant Human ENDOG, His-tagged

• Cat.No.: ENDOG-12448H
• Product Overview: Recombinant Human ENDOG protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: The protein encoded by this gene is a nuclear encoded endonuclease that is localized in the mitochondrion. The encoded protein is widely distributed among animals and cleaves DNA at GC tracts. This protein is capable of generating the RNA primers required by DNA polymerase gamma to initiate replication of mitochondrial DNA.
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 63-297a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: ENDOG endonuclease G [ Homo sapiens ]
• Official Symbol: ENDOG
• Synonyms: ENDOG; endonuclease G; endonuclease G, mitochondrial; endo G; mitochondrial endonuclease G; FLJ27463
• Gene ID: 2021
• mRNA Refseq: NM_004435
• Protein Refseq: NP_004426
• MIM: 600440
• UniProt ID: Q14249
• Chromosome Location: 9q34.1
• Pathway: Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem
• Function: endonuclease activity; hydrolase activity; metal ion binding; nucleic acid binding