Recombinant Human ESX1, His-tagged ESX1-12563H

Recombinant Human ESX1, His-tagged

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Recombinant Human ESX1, His-tagged

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Cat.No. : ESX1-12563H
Product Overview : Recombinant Human ESX1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description : This gene encodes a dual-function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N-terminal fragment with a paired-like homeodomain and a 20 kDa C-terminal fragment with a proline-rich domain. The C-terminal fragment localizes to the cytoplasm while the N-terminal fragment localizes exclusively to the nucleus. In contrast to human, the mouse homolog has a novel PN/PF motif in the C-terminus and is paternally imprinted in placental tissue. This gene likely plays a role in placental development and spermatogenesis.
Source : E.coli
Species : Human
Tag : His
Protein length : 1-406a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : ESX1 ESX homeobox 1 [ Homo sapiens ]
Official Symbol : ESX1
Synonyms : ESX1; ESX homeobox 1; ESX1L, extraembryonic, spermatogenesis, homeobox 1 homolog (mouse); homeobox protein ESX1; ESXR1; ESX1-related protein; extraembryonic, spermatogenesis, homeobox 1 homolog; ESX1L;
Gene ID : 80712
mRNA Refseq : NM_153448
Protein Refseq : NP_703149
MIM : 300154
UniProt ID : Q8N693
Chromosome Location : Xq22.2
Function : sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity;

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◆ Recombinant Protein

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