Recombinant Human F2 Protein, His-tagged F2-12619H

Recombinant Human F2 Protein, His-tagged

PRODUCTS

Home / Products / Recombinant Human F2 Protein, His-tagged

Recombinant Human F2 Protein, His-tagged

F2 Related Products

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.

Cat.No. : F2-12619H
Product Overview : Recombinant Human F2 Protein(NP_000497.1)(Ala44~Arg198) is expressed from E. coli with a His tag at the N-terminal.
Description : This gene encodes the prothrombin protein (also known as coagulation factor II). This protein is proteolytically cleaved in multiple steps to form the activated serine protease thrombin. The activated thrombin enzyme plays an important role in thrombosis and hemostasis by converting fibrinogen to fibrin during blood clot formation, by stimulating platelet aggregation, and by activating additional coagulation factors. Thrombin also plays a role in cell proliferation, tissue repair, and angiogenesis as well as maintaining vascular integrity during development and postnatal life. Peptides derived from the C-terminus of this protein have antimicrobial activity against E. coli and P. aeruginosa. Mutations in this gene lead to various forms of thrombosis and dysprothrombinemia. Rapid increases in cytokine levels following coronavirus infections can dysregulate the coagulation cascade and produce thrombosis, compromised blood supply, and organ failure.
Source : E. coli
Species : Human
Tag : His
Form : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Molecular Mass : The predicted molecular mass is 20.9kDa.
Protein length : Ala44~Arg198
AA Sequence : MGSSHHHHHHSSGLV PRGSHMASMTGGQQM GRGSANTFLEEVRKG NLERECVEETCSYEE AFEALESSTATDVFW AKYTACETARTPRDK LAACLEGNCAEGLGT NYRGHVNITRSGIEC QLWRSRYPHKPEINS TTHPGADLQENFCRN PDSSTTGPWCYTTDP TVRRQECSIPVCGQD QVTVAMTPR
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : > 95%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
SDS-PAGE of F2-12619H :

Gene Name : F2
Official Symbol : F2
Synonyms : FII; TM; PT; Thrombin; Prothrombin; Pro-Thrombin; Activation peptide fragment 1; Activation peptide fragment 2
Gene ID : 2147
mRNA Refseq : NM_000506.5
Protein Refseq : NP_000497.1
MIM : 176930
UniProt ID : P00734

Online Inquiry


  • Note: There will be extra charge for optional service!
  • Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional Service: Optional requirements on this protein

Other Requirements:

Apply For A Coupon

$50 OFF Your First Purchase

Apply For a Coupon

Enter your email here to subscribe.

creative biomart inc.

Easy access to products and services you need from our library via powerful searching tools.

Follow Us

Copyright © 2007 – 2020 Creative BioMart. All Rights Reserved. Terms and Conditions | Privacy Policy