"FANCG" Related Products

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Recombinant Human FANCG, His-tagged

Cat.No.: FANCG-12739H
Product Overview: Recombinant Human FANCG protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group G.
Source: E.coli
Species: Human
Tag: His
Protein length: 125-348a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: FANCG Fanconi anemia, complementation group G [ Homo sapiens ]
Official Symbol: FANCG
Synonyms: FANCG; Fanconi anemia, complementation group G; XRCC9; Fanconi anemia group G protein; DNA repair protein XRCC9; FAG; X ray repair complementing defective repair in Chinese hamster cells 9; X ray repair; complementing defective; in Chinese hamster; 9; X-ray repair, complementing defective, in Chinese hamster, 9; X-ray repair complementing defective repair in Chinese hamster cells 9;
Gene ID: 2189
mRNA Refseq: NM_004629
Protein Refseq: NP_004620
MIM: 602956
UniProt ID: O15287
Chromosome Location: 9p13
Pathway: BARD1 signaling events, organism-specific biosystem; DNA Repair, organism-specific biosystem; FA core complex, organism-specific biosystem; Fanconi Anemia pathway, organism-specific biosystem; Fanconi anemia pathway, organism-specific biosystem; Fanconi anemia pathway, conserved biosystem;
Function: damaged DNA binding; protein binding;

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