Recombinant Human FBXL21, His-tagged FBXL21-12779H

Recombinant Human FBXL21, His-tagged


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Recombinant Human FBXL21, His-tagged

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Cat.No. : FBXL21-12779H
Product Overview : Recombinant Human FBXL21 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description : This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains 6 tandem leucine-rich repeats. The amino acid sequence of this protein is highly similar to that of f-box and leucine-rich repeat protein 3A. Comparisons of this gene to orthologous sequences suggest that it may be a pseudogene, and may no longer express a functional protein.
Source : E.coli
Species : Human
Tag : His
Protein length : C-term-214a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : FBXL21 F-box and leucine-rich repeat protein 21 (gene/pseudogene) [ Homo sapiens ]
Official Symbol : FBXL21
Synonyms : FBXL21; F-box and leucine-rich repeat protein 21 (gene/pseudogene); F box and leucine rich repeat protein 3 pseudogene , F box and leucine rich repeat protein 21 , FBXL3B, FBXL3P; F-box/LRR-repeat protein 21; F box and leucine rich repeat protein 3B; FBL3B; Fbl21; F-box protein Fbl3b; F-box/LRR-repeat protein 3B; F-box and leucine-rich repeat protein 3B; F-box and leucine-rich repeat protein 3 pseudogene; FBXL3B; FBXL3P; MGC120237;
Gene ID : 26223
mRNA Refseq : NM_012159
Protein Refseq : NP_036291
MIM : 609087
UniProt ID : Q9UKT6
Chromosome Location : 5q31
Function : ubiquitin-protein ligase activity;

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