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Recombinant Human FBXL5, His-tagged

Cat.No. : FBXL5-12780H
Product Overview : Recombinant Human FBXL5 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
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Description : This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternatively spliced transcript variants have been described for this locus.
Source : E.coli
Species : Human
Tag : His
Protein length : 1-250a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : FBXL5 F-box and leucine-rich repeat protein 5 [ Homo sapiens ]
Official Symbol : FBXL5
Synonyms : FBXL5; F-box and leucine-rich repeat protein 5; F-box/LRR-repeat protein 5; FBL4; FBL5; FLR1; F-box protein FBL5; p45SKP2-like protein; F-box protein FBL4/FBL5;
Gene ID : 26234
mRNA Refseq : NM_001193534
Protein Refseq : NP_001180463
MIM : 605655
UniProt ID : Q9UKA1
Chromosome Location : 4p15.33
Pathway : Association of TriC/CCT with target proteins during biosynthesis, organism-specific biosystem; Chaperonin-mediated protein folding, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; Protein folding, organism-specific biosystem;
Function : iron ion binding; metal ion binding; protein binding; ubiquitin-protein ligase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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