"FBXL5" Related Products

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Recombinant Human FBXL5, His-tagged

Cat.No.: FBXL5-12780H
Product Overview: Recombinant Human FBXL5 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains several tandem leucine-rich repeats. Alternatively spliced transcript variants have been described for this locus.
Source: E.coli
Species: Human
Tag: His
Protein length: 1-250a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: FBXL5 F-box and leucine-rich repeat protein 5 [ Homo sapiens ]
Official Symbol: FBXL5
Synonyms: FBXL5; F-box and leucine-rich repeat protein 5; F-box/LRR-repeat protein 5; FBL4; FBL5; FLR1; F-box protein FBL5; p45SKP2-like protein; F-box protein FBL4/FBL5;
Gene ID: 26234
mRNA Refseq: NM_001193534
Protein Refseq: NP_001180463
MIM: 605655
UniProt ID: Q9UKA1
Chromosome Location: 4p15.33
Pathway: Association of TriC/CCT with target proteins during biosynthesis, organism-specific biosystem; Chaperonin-mediated protein folding, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; Protein folding, organism-specific biosystem;
Function: iron ion binding; metal ion binding; protein binding; ubiquitin-protein ligase activity;

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