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Recombinant Human FBXO44, GST-tagged

Cat.No. : FBXO44-12802H
Product Overview : Recombinant Human FBXO44 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
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Description : This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It is also a member of the NFB42 (neural F Box 42 kDa) family, similar to F-box only protein 2 and F-box only protein 6. Four alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene.
Source : E.coli
Species : Human
Tag : GST
Protein length : 1-224a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : FBXO44 F-box protein 44 [ Homo sapiens ]
Official Symbol : FBXO44
Synonyms : F-box protein 44; 24847; Ensembl:ENSG00000132879; MGC14140, DKFZp781J0852; F-box only protein 44;F-box gene 3;F-box protein FBX30;F-box/G-domain protein 3; FBG3; FBX30; FBX6A; Fbx44; Fbxo6a
Gene ID : 93611
mRNA Refseq : NM_001014765.1
Protein Refseq : NP_001014765.1
MIM : 609111
UniProt ID : Q9H4M3
Chromosome Location : 1p36.22
Pathway : Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem;
Function : protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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