Recombinant Human FECH, His-tagged
Cat.No. : | FECH-12837H |
Product Overview : | Recombinant Human FECH protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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Description : | The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 60-423a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | FECH ferrochelatase [ Homo sapiens ] |
Official Symbol : | FECH |
Synonyms : | FECH; ferrochelatase; ferrochelatase (protoporphyria); ferrochelatase, mitochondrial; protoporphyria; heme synthase; heme synthetase; protoheme ferro-lyase; EPP; FCE; |
Gene ID : | 2235 |
mRNA Refseq : | NM_000140 |
Protein Refseq : | NP_000131 |
MIM : | 612386 |
UniProt ID : | P22830 |
Chromosome Location : | 18q21.2-q21.3 |
Pathway : | HIF-1-alpha transcription factor network, organism-specific biosystem; Heme Biosynthesis, organism-specific biosystem; Heme biosynthesis, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of porphyrins, organism-specific biosystem; Porphyrin and chlorophyll metabolism, organism-specific biosystem; |
Function : | 2 iron, 2 sulfur cluster binding; ferrochelatase activity; ferrochelatase activity; ferrous iron binding; metal ion binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
FECH-4065H | Recombinant Human FECH Protein, GST-tagged | +Inquiry |
FECH-905H | Recombinant Human FECH Protein, His (Fc)-Avi-tagged | +Inquiry |
Fech-2984M | Recombinant Mouse Fech Protein, Myc/DDK-tagged | +Inquiry |
FECH-01H | Recombinant human FECH protein, C-Myc/DDK-tagged | +Inquiry |
FECH-2316H | Recombinant Human FECH Protein (Gly55-Gln422), N-His tagged | +Inquiry |
◆ Lysates | ||
FECH-6267HCL | Recombinant Human FECH 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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