"FKBP3" Related Products

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Recombinant Human FKBP3, GST-tagged

Cat.No.: FKBP3-12912H
Product Overview: Recombinant Human FKBP3 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description: The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin.
Source: E.coli
Species: Human
Tag: GST
Protein length: 1-224a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name: FKBP3 FK506 binding protein 3, 25kDa [ Homo sapiens ]
Official Symbol: FKBP3
Synonyms: FKBP3; FK506 binding protein 3, 25kDa; FK506 binding protein 3 (25kD); peptidyl-prolyl cis-trans isomerase FKBP3; FKBP 25; PPIase; rotamase; 25 kDa FKBP; PPIase FKBP3; immunophilin FKBP25; rapamycin binding protein; 25 kDa FK506-binding protein; FK506-binding protein 3 (25kD); FK506-binding protein 25, T-cell; rapamycin-selective 25 kDa immunophilin; FKBP-3; FKBP25; FKBP-25;
Gene ID: 2287
mRNA Refseq: NM_002013
Protein Refseq: NP_002004
MIM: 186947
UniProt ID: Q00688
Chromosome Location: 14q21.2
Pathway: Signaling events mediated by HDAC Class I, organism-specific biosystem;
Function: FK506 binding; isomerase activity; peptidyl-prolyl cis-trans isomerase activity; receptor activity;

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