Recombinant Human FKBP3, GST-tagged
Cat.No. : | FKBP3-12912H |
Product Overview : | Recombinant Human FKBP3 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-224a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | FKBP3 FK506 binding protein 3, 25kDa [ Homo sapiens ] |
Official Symbol : | FKBP3 |
Synonyms : | FKBP3; FK506 binding protein 3, 25kDa; FK506 binding protein 3 (25kD); peptidyl-prolyl cis-trans isomerase FKBP3; FKBP 25; PPIase; rotamase; 25 kDa FKBP; PPIase FKBP3; immunophilin FKBP25; rapamycin binding protein; 25 kDa FK506-binding protein; FK506-binding protein 3 (25kD); FK506-binding protein 25, T-cell; rapamycin-selective 25 kDa immunophilin; FKBP-3; FKBP25; FKBP-25; |
Gene ID : | 2287 |
mRNA Refseq : | NM_002013 |
Protein Refseq : | NP_002004 |
MIM : | 186947 |
UniProt ID : | Q00688 |
Chromosome Location : | 14q21.2 |
Pathway : | Signaling events mediated by HDAC Class I, organism-specific biosystem; |
Function : | FK506 binding; isomerase activity; peptidyl-prolyl cis-trans isomerase activity; receptor activity; |
Products Types
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FKBP3-4190H | Recombinant Human FKBP3 Protein, GST-tagged | +Inquiry |
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FKBP3-6936H | Recombinant Human FKBP3, GST tagged | +Inquiry |
◆ Lysates | ||
FKBP3-6206HCL | Recombinant Human FKBP3 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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