Recombinant Human FSHR, His-tagged

• Cat.No.: FSHR-13016H
• Product Overview: Recombinant Human FSHR protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: The protein encoded by this gene belongs to family 1 of G-protein coupled receptors. It is the receptor for follicle stimulating hormone and functions in gonad development. Mutations in this gene cause ovarian dysgenesis type 1, and also ovarian hyperstimulation syndrome. Alternative splicing results in multiple transcript variants.
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 18-352a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: FSHR follicle stimulating hormone receptor [ Homo sapiens ]
• Official Symbol: FSHR
• Synonyms: FSHR; follicle stimulating hormone receptor; ODG1; follicle-stimulating hormone receptor; FSHRO; LGR1; FSH receptor; follitropin receptor; MGC141667; MGC141668
• Gene ID: 2492
• mRNA Refseq: NM_000145
• Protein Refseq: NP_000136
• MIM: 136435
• UniProt ID: P23945
• Chromosome Location: 2p21-p16
• Pathway: Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; GPCRs, Other, organism-specific biosystem; Hormone ligand-binding receptors, organism-specific biosystem
• Function: follicle-stimulating hormone receptor activity; peptide hormone binding; protein binding; receptor activity; signal transducer activity