Recombinant Human GABARAP, GST-tagged
Cat.No. : | GABARAP-13085H |
Product Overview : | Recombinant Human GABARAP protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | Gamma-aminobutyric acid A receptors [GABA(A) receptors] are ligand-gated chloride channels that mediate inhibitory neurotransmission. This gene encodes GABA(A) receptor-associated protein, which is highly positively charged in its N-terminus and shares sequence similarity with light chain-3 of microtubule-associated proteins 1A and 1B. This protein clusters neurotransmitter receptors by mediating interaction with the cytoskeleton. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-117a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | GABARAP GABA(A) receptor-associated protein [ Homo sapiens ] |
Official Symbol : | GABARAP |
Synonyms : | GABARAP; GABA(A) receptor-associated protein; gamma-aminobutyric acid receptor-associated protein; ATG8A; MM46; GABARAP-a; FLJ25768; MGC120154; MGC120155; |
Gene ID : | 11337 |
mRNA Refseq : | NM_007278 |
Protein Refseq : | NP_009209 |
MIM : | 605125 |
UniProt ID : | O95166 |
Chromosome Location : | 17p13.1 |
Pathway : | GABAergic synapse, organism-specific biosystem; GABAergic synapse, conserved biosystem; Regulation of autophagy, organism-specific biosystem; Regulation of autophagy, conserved biosystem; Senescence and Autophagy, organism-specific biosystem; |
Function : | GABA receptor binding; beta-tubulin binding; microtubule binding; protein binding; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionGABARAP contributes to protein aggregation and degradation processes, crucial in maintaining cellular health.
GABARAP impacts GABA receptor trafficking and surface expression, affecting receptor availability and signaling.
GABARAP plays a role in immune cell functioning and modulates inflammatory responses.
GABARAP is involved in autophagy, aiding in the degradation and recycling of cellular components for homeostasis.
GABARAP is linked to the pathology of neurological disorders, potentially affecting protein aggregation and neuronal function.
GABARAP regulates neuronal signaling, particularly at GABAergic synapses, influencing neurotransmission.
Changes in GABARAP expression influence cancer cell behavior, impacting growth, survival, and responsiveness to therapy.
Customer Reviews (3)
Write a reviewPrecise protein quantification, fundamental for our studies' accuracy.
Efficient protein purification, consistent yields, cost-effective service.
Dependable peptide synthesis, accelerates our peptide-based projects.
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