"GABRG2" Related Products

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Recombinant Human GABRG2, His-tagged

Cat.No.: GABRG2-13103H
Product Overview: Recombinant Human GABRG2 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: This gene encodes a gamma-aminobutyric acid (GABA) receptor. GABA is the major inhibitory neurotransmitter in the mammlian brain, where it acts at GABA-A receptors, which are ligand-gated chloride channels. GABA-A receptors are pentameric, consisting of proteins from several subunit classes: alpha, beta, gamma, delta and rho. Mutations in this gene have been associated with epilepsy and febrile seizures. Multiple transcript variants encoding different isoforms have been identified for this gene.
Source: E.coli
Species: Human
Tag: His
Protein length: 40-273a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: GABRG2 gamma-aminobutyric acid (GABA) A receptor, gamma 2 [ Homo sapiens ]
Official Symbol: GABRG2
Synonyms: GABRG2; gamma-aminobutyric acid (GABA) A receptor, gamma 2; gamma-aminobutyric acid receptor subunit gamma-2; GABA(A) receptor; gamma 2; GABA(A) receptor, gamma 2; GABA(A) receptor subunit gamma-2; CAE2; ECA2; GEFSP3;
Gene ID: 2566
mRNA Refseq: NM_000816
Protein Refseq: NP_000807
MIM: 137164
UniProt ID: P18507
Chromosome Location: 5q34
Pathway: GABA A receptor activation, organism-specific biosystem; GABA receptor activation, organism-specific biosystem; GABAergic synapse, organism-specific biosystem; GABAergic synapse, conserved biosystem; Ion channel transport, organism-specific biosystem; Ligand-gated ion channel transport, organism-specific biosystem; Morphine addiction, organism-specific biosystem;
Function: GABA-A receptor activity; benzodiazepine receptor activity; chloride channel activity; extracellular ligand-gated ion channel activity; ion channel activity; protein binding;

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