"GLDC" Related Products

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Recombinant Human GLDC, His-tagged

Cat.No.: GLDC-13294H
Product Overview: Recombinant Human GLDC protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: The protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene.
Source: E.coli
Species: Human
Tag: His
Protein length: 675-1020a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: GLDC glycine dehydrogenase (decarboxylating) [ Homo sapiens ]
Official Symbol: GLDC
Synonyms: GLDC; glycine dehydrogenase (decarboxylating); glycine dehydrogenase (decarboxylating; glycine decarboxylase, glycine cleavage system protein P); glycine dehydrogenase [decarboxylating], mitochondrial; GCSP; glycine cleavage system protein P; glycine decarboxylase; NKH; glycine decarboxylase P-protein; glycine cleavage system P protein; GCE; HYGN1; MGC138198; MGC138200;
Gene ID: 2731
mRNA Refseq: NM_000170
Protein Refseq: NP_000161
MIM: 238300
UniProt ID: P23378
Chromosome Location: 9p22
Pathway: Glycine, serine and threonine metabolism, organism-specific biosystem; Glycine, serine and threonine metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; glycine cleavage complex, organism-specific biosystem;
Function: electron carrier activity; glycine dehydrogenase (decarboxylating) activity; lyase activity; oxidoreductase activity; pyridoxal phosphate binding;

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