Recombinant Human GLDC Protein, GST-tagged GLDC-4950H

Recombinant Human GLDC Protein, GST-tagged

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Recombinant Human GLDC Protein, GST-tagged

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Cat.No. : GLDC-4950H
Product Overview : Human GLDC partial ORF ( NP_000161.1, 922 a.a. - 1020 a.a.) recombinant protein with GST-tag at N-terminal.
Description : The enzyme system for cleavage of glycine (glycine cleavage system; GCS; EC 2.1.2.10), which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). Glycine encephalopathy (GCE; MIM 605899) may be due to a defect in any one of these enzymes; see MIM 238310, MIM 238330, and MIM 238331.[supplied by OMIM
Source : Wheat Germ
Species : Human
Tag : GST
Molecular Mass : 36.63 kDa
AA Sequence : AMISIRQEIA DIEEGRIDPR VNPLKMSPHS LTCVTSSHWD RPYSREVAAF PLPFMKPENK FWPTIARIDD IYGDQHLVCT CPPMEVYESP FSEQKRASS
Applications : Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Storage Buffer : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Quality Control Testing :

12.5% SDS-PAGE Stained with Coomassie Blue.

Gene Name : GLDC glycine dehydrogenase (decarboxylating) [ Homo sapiens ]
Official Symbol : GLDC
Synonyms : GLDC; glycine dehydrogenase (decarboxylating); glycine dehydrogenase (decarboxylating; glycine decarboxylase, glycine cleavage system protein P); glycine dehydrogenase [decarboxylating], mitochondrial; GCSP; glycine cleavage system protein P; glycine decarboxylase; NKH; glycine decarboxylase P-protein; glycine cleavage system P protein; GCE; HYGN1; MGC138198; MGC138200;
Gene ID : 2731
mRNA Refseq : NM_000170
Protein Refseq : NP_000161
MIM : 238300
UniProt ID : P23378

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