Recombinant Human GSDMD protein, His-tagged
Cat.No. : | GSDMD-13558H |
Product Overview : | Recombinant Human GSDMD protein(135-484 aa), fused with His tag, was expressed in E.coli. |
Unit | |
Price | |
Qty |
- Specification
- Gene Information
- Related Products
Source : | E.coli |
Species : | Human |
Tag : | His |
Form : | The purified protein was Lyophilized from sterile PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH7.4). 5 % trehalose and 5 % mannitol are added as protectant before lyophilization. The elution buffer contain 300mM imidazole. |
Protein Length : | 135-484 aa |
AA Sequence : | HERHLRQPEHKVLQQLRSRGDNVYV VTEVLQTQKEVEVTRTHKREGSGRF SLPGATCLQGEGQGHLSQKKTVTIP SGSTLAFRVAQLVIDSDLDVLLFPD KKQRTFQPPATGHKRSTSEGAWPQL PSGLSMMRCLHNFLTDGVPAEGAFT EDFQGLRAEVETISKELELLDRELC QLLLEGLEGVLRDQLALRALEEALE QGQSLGPVEPLDGPAGAVLECLVLS SGMLVPELAIPVVYLLGALTMLSET QHKLLAEALESQTLLGPLELVGSLL EQSAPWQERSTMSLPPGLLGNSWGE GAPAWVLLDECGLELGEDTPHVCWE PQAQGRMCALYASLALLSGLSQEPH |
Purity : | 85%, by SDS-PAGE with Coomassie Brilliant Blue staining. |
Storage : | Short-term storage: Store at 2-8°C for (1-2 weeks). Long-term storage: Aliquot and store at -20°C to -80°C for up to 3 months, buffer containing 50% glycerol is recommended for reconstitution. Avoid repeat freeze-thaw cycles. |
Reconstitution : | Reconstitute at 0.25 µg/μl in 200 μl sterile water for short-term storage. Reconstitution with 200 μl 50% glycerol solution is recommended for longer term storage. |
Gene Name : | GSDMD gasdermin D [ Homo sapiens ] |
Official Symbol : | GSDMD |
Synonyms : | GSDMD; gasdermin D; gasdermin domain containing 1 , GSDMDC1; gasdermin-D; DF5L; FLJ12150; gasdermin domain containing 1; gasdermin domain-containing protein 1; DFNA5L; FKSG10; GSDMDC1; |
Gene ID : | 79792 |
mRNA Refseq : | NM_001166237 |
Protein Refseq : | NP_001159709 |
UniProt ID : | P57764 |
Products Types
◆ Recombinant Protein | ||
Gsdmd-1600M | Recombinant Mouse Gsdmd Protein, His-tagged | +Inquiry |
Gsdmd-1601R | Recombinant Rat Gsdmd Protein, His-tagged | +Inquiry |
GSDMD-2218H | Recombinant Human GSDMD Protein, His-tagged | +Inquiry |
GSDMD-3957M | Recombinant Mouse GSDMD Protein, His (Fc)-Avi-tagged | +Inquiry |
GSDMD-7312M | Recombinant Mouse GSDMD Protein | +Inquiry |
◆ Lysates | ||
GSDMD-5725HCL | Recombinant Human GSDMD 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (5)
Ask a questionStudies have suggested that the expression levels of GSDMD protein may be associated with disease severity and prognosis in certain inflammatory conditions, indicating its potential as a prognostic marker.
Mutations in the GSDMD gene have been associated with autoinflammatory disorders, such as familial Mediterranean fever, which presents with recurrent episodes of fever and inflammation.
Various signaling pathways and post-translational modifications regulate the activity of GSDMD protein, contributing to its involvement in the pathogenesis of inflammatory diseases.
The inflammasome, a multiprotein complex that regulates inflammatory responses, activates GSDMD protein to induce pyroptosis and release of pro-inflammatory cytokines, contributing to the pathogenesis of inflammatory diseases.
Targeting GSDMD protein could lead to the development of diagnostic tools for detecting and monitoring inflammatory diseases, providing valuable insights for patient management.
Customer Reviews (3)
Write a reviewWhether I need to study protein-protein interactions, protein localization, or protein folding, the GSDMD protein consistently delivers precise and meaningful data.
the GSDMD protein's compatibility with various experimental techniques further supports its usability.
One of the standout features of the GSDMD protein is the excellent technical support provided by the manufacturer.
Ask a Question for All GSDMD Products
Required fields are marked with *
My Review for All GSDMD Products
Required fields are marked with *
Inquiry Basket