"GUCY1B3" Related Products

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Recombinant Human GUCY1B3, His-tagged

Cat.No. : GUCY1B3-13619H
Product Overview : Recombinant Human GUCY1B3 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description : Soluble guanylate cyclase (sGC), a heterodimeric protein consisting of an alpha subunit and a beta subunit, typically GUCY1B3, catalyzes conversion of GTP to the second messenger cGMP and functions as the main receptor for nitric oxide (NO) and nitrovasodilator drugs (Zabel et al., 1998 [PubMed 9742212]).
Source : E.coli
Species : Human
Tag : His
Protein length : 282-619a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : GUCY1B3 guanylate cyclase 1, soluble, beta 3 [ Homo sapiens ]
Official Symbol : GUCY1B3
Synonyms : GUCY1B3; guanylate cyclase 1, soluble, beta 3; GUC1B3; guanylate cyclase soluble subunit beta-1; GC S beta 1; GC SB3; GCS-beta-1; GCS-beta-3; soluble guanylate cyclase small subunit; guanylate cyclase soluble subunit beta-3; GUCB3; GC-SB3; GUCSB3; GUCY1B1; GC-S-beta-1;
Gene ID : 2983
mRNA Refseq : NM_000857
Protein Refseq : NP_000848
MIM : 139397
UniProt ID : Q02153
Chromosome Location : 4q31.3-q33
Pathway : Gap junction, organism-specific biosystem; Gap junction, conserved biosystem; Hemostasis, organism-specific biosystem; Long-term depression, organism-specific biosystem; Long-term depression, conserved biosystem; Nitric oxide stimulates guanylate cyclase, organism-specific biosystem; Platelet homeostasis, organism-specific biosystem;
Function : GTP binding; Hsp90 protein binding; guanylate cyclase activity; heme binding; ion binding; metal ion binding; nucleotide binding; protein heterodimerization activity; receptor activity;

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