"HDAC7" Related Products


Recombinant Human HDAC7, His-tagged

Cat.No.: HDAC7-13710H
Product Overview: Recombinant Human HDAC7 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Source: E.coli
Species: Human
Tag: His
Protein length: C-term--276a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: HDAC7 histone deacetylase 7 [ Homo sapiens ]
Official Symbol: HDAC7
Synonyms: HDAC7; histone deacetylase 7; HDAC7A, histone deacetylase 7A; DKFZP586J0917; HD7; histone deacetylase 7A; HD7A; HDAC7A; FLJ99588; DKFZp586J0917;
Gene ID: 51564
mRNA Refseq: NM_001098416
Protein Refseq: NP_001091886
MIM: 606542
UniProt ID: Q8WUI4
Chromosome Location: 12q13.1
Pathway: B Cell Receptor Signaling Pathway, organism-specific biosystem; Cell cycle, organism-specific biosystem; HIF-1-alpha transcription factor network, organism-specific biosystem; MicroRNAs in cardiomyocyte hypertrophy, organism-specific biosystem; NOTCH1 Intracellular Domain Regulates Transcription, organism-specific biosystem; Regulation of Androgen receptor activity, organism-specific biosystem; Signal Transduction, organism-specific biosystem;
Function: 14-3-3 protein binding; NAD-dependent histone deacetylase activity (H3-K14 specific); NAD-dependent histone deacetylase activity (H3-K9 specific); NAD-dependent histone deacetylase activity (H4-K16 specific); activating transcription factor binding; chrom

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