Recombinant Human HERC3, GST-tagged

• Cat.No.: HERC3-13738H
• Product Overview: Recombinant Human HERC3 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-368a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3 [ Homo sapiens ]
• Official Symbol: HERC3
• Synonyms: HERC3; HECT and RLD domain containing E3 ubiquitin protein ligase 3; hect domain and RLD 3; probable E3 ubiquitin-protein ligase HERC3; KIAA0032; HECT domain and RCC1-like domain-containing protein 3
• Gene ID: 8916
• mRNA Refseq: NM_014606
• Protein Refseq: NP_055421
• MIM: 605200
• UniProt ID: Q15034
• Chromosome Location: 4q21
• Pathway: Ubiquitin mediated proteolysis, organism-specific biosystem; Ubiquitin mediated proteolysis, conserved biosystem
• Function: acid-amino acid ligase activity; ligase activity; ubiquitin-protein ligase activity