Recombinant Human HEYL, His-tagged HEYL-13757H

Recombinant Human HEYL, His-tagged

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Recombinant Human HEYL, His-tagged

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Cat.No. : HEYL-13757H
Product Overview : Recombinant Human HEYL protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description : This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The sequence of the encoded protein contains a conserved bHLH and orange domain, but its YRPW motif has diverged from other HESR family members. It is thought to be an effector of Notch signaling and a regulator of cell fate decisions. Alternatively spliced transcript variants have been found, but their biological validity has not been determined.
Source : E.coli
Species : Human
Tag : His
Protein length : 1-328a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : HEYL hairy/enhancer-of-split related with YRPW motif-like [ Homo sapiens ]
Official Symbol : HEYL
Synonyms : HEYL; hairy/enhancer-of-split related with YRPW motif-like; hairy/enhancer-of-split related with YRPW motif-like protein; bHLHb33; hairy/enhancer of split related with YRPW motif 3; HEY3; HRT-3; hHRT3; hHeyL; HEY-like protein; hairy-related transcription factor 3; class B basic helix-loop-helix protein 33; hairy/enhancer-of-split related with YRPW motif 3; HRT3; MGC12623;
Gene ID : 26508
mRNA Refseq : NM_014571
Protein Refseq : NP_055386
MIM : 609034
UniProt ID : Q9NQ87
Chromosome Location : 1p34.3
Pathway : NOTCH1 Intracellular Domain Regulates Transcription, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by NOTCH, organism-specific biosystem; Signaling by NOTCH1, organism-specific biosystem;
Function : AF-1 domain binding; DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription; RNA polymerase II core promoter sequence-specific DNA binding;

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