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Recombinant Human HIST1H4E, GST-tagged

Cat.No. : HIST1H4E-13798H
Product Overview : Recombinant Human HIST1H4E protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
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Description : Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H4 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
Source : E.coli
Species : Human
Tag : GST
Protein length : 1-103a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : HIST1H4E histone cluster 1, H4e [ Homo sapiens ]
Official Symbol : HIST1H4E
Synonyms : histone cluster 1, H4e; 4790; Ensembl:ENSG00000198518; histone H4;histone 1, H4e;H4 histone family, member J; H4/j; H4FJ
Gene ID : 8367
mRNA Refseq : NM_003545.3
Protein Refseq : NP_003536.1
MIM : 602830
UniProt ID : B2R4R0
Chromosome Location : 6p22.1
Pathway : Alcoholism, organism-specific biosystem; Alcoholism, conserved biosystem; Amyloids, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Chromosome Maintenance, organism-specific biosystem; Deposition of New CENPA-containing Nucleosomes at the Centromere, organism-specific biosystem; Disease, organism-specific biosystem;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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