Recombinant Human HLA-G, GST-tagged HLA-G-13828H

Recombinant Human HLA-G, GST-tagged

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Recombinant Human HLA-G, GST-tagged

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Cat.No. : HLA-G-13828H
Product Overview : Recombinant Human HLA-G protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description : HLA-G belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. HLA-G is expressed on fetal derived placental cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domain, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exon 6 encodes the cytoplasmic tail.
Source : E.coli
Species : Human
Tag : GST
Protein length : 26-308a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : HLA-G major histocompatibility complex, class I, G [ Homo sapiens ]
Official Symbol : HLA-G
Synonyms : HLA-G; major histocompatibility complex, class I, G; HLA G histocompatibility antigen, class I, G; HLA class I histocompatibility antigen, alpha chain G; b2 microglobulin; HLA G antigen; HLA class I molecule; MHC class I antigen G; HLA-G histocompatibility antigen, class I, G; MHC-G;
Gene ID : 3135
mRNA Refseq : NM_002127
Protein Refseq : NP_002118
MIM : 142871
UniProt ID : P17693
Chromosome Location : 6p21.3
Pathway : Adaptive Immune System, organism-specific biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Antigen Presentation: Folding, assembly and peptide loading of class I MHC, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Antigen processing-Cross presentation, organism-specific biosystem;
Function : MHC class I receptor activity; protein homodimerization activity; receptor binding;

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