"HMBS" Related Products


Recombinant Human HMBS, GST-tagged

Cat.No.: HMBS-13835H
Product Overview: Recombinant Human HMBS protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
Description: This gene encodes a member of the hydroxymethylbilane synthase superfamily. The encoded protein is the third enzyme of the heme biosynthetic pathway and catalyzes the head to tail condensation of four porphobilinogen molecules into the linear hydroxymethylbilane. Mutations in this gene are associated with the autosomal dominant disease acute intermittent porphyria. Alternatively spliced transcript variants encoding different isoforms have been described.
Source: E.coli
Species: Human
Tag: GST
Protein length: 1-361a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name: HMBS hydroxymethylbilane synthase [ Homo sapiens ]
Official Symbol: HMBS
Synonyms: HMBS; hydroxymethylbilane synthase; PBGD, PORC, porphobilinogen deaminase , porphyria, acute; Chester type , UPS, uroporphyrinogen I synthase; porphobilinogen deaminase; uroporphyrinogen I synthase; pre-uroporphyrinogen synthase; uroporphyrinogen I synthetase; porphyria, acute; Chester type; UPS; PBGD; PORC; PBG-D;
Gene ID: 3145
mRNA Refseq: NM_000190
Protein Refseq: NP_000181
MIM: 609806
UniProt ID: P08397
Chromosome Location: 11q23.2-qter
Pathway: Heme Biosynthesis, organism-specific biosystem; Heme biosynthesis, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of porphyrins, organism-specific biosystem; Porphyrin and chlorophyll metabolism, organism-specific biosystem; Porphyrin and chlorophyll metabolism, conserved biosystem;
Function: amine binding; carboxylic acid binding; coenzyme binding; hydroxymethylbilane synthase activity; hydroxymethylbilane synthase activity; transferase activity; uroporphyrinogen-III synthase activity;

Online Inquiry

Note: There will be extra charge for optional service!

Please input "biomart" as verification code. Please review Creative BioMart's privacy policy for more information

Optional requirements on this protein    +Expand

Price Inquiry

Welcome! For price inquiries, please feel free to contact us through the form below. We will get back to you as soon as possible.