"HOMER3" Related Products


Recombinant Human HOMER3, His-tagged

Cat.No.: HOMER3-13881H
Product Overview: Recombinant Human HOMER3 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
Description: This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.
Source: E.coli
Species: Human
Tag: His
Protein length: 1-361a.a.
Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name: HOMER3 homer homolog 3 (Drosophila) [ Homo sapiens ]
Official Symbol: HOMER3
Synonyms: HOMER3; homer homolog 3 (Drosophila); homer protein homolog 3; HOMER 3; Homer, neuronal immediate early gene, 3; VESL3; HOMER-3;
Gene ID: 9454
mRNA Refseq: NM_001145721
Protein Refseq: NP_001139193
MIM: 604800
UniProt ID: Q9NSC5
Chromosome Location: 19p13.1
Pathway: Glutamatergic synapse, organism-specific biosystem; Glutamatergic synapse, conserved biosystem; T Cell Receptor Signaling Pathway, organism-specific biosystem;
Function: protein C-terminus binding; protein binding; protein domain specific binding;

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