Recombinant Human STX6, His-tagged

• Cat.No.: STX6-2343H
• Product Overview: Recombinant human STX6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: STX6 belongs to the syntaxin family and contains 1 t-SNARE coiled-coil homology domain. This protein is involved in intracellular vesicle trafficking. STX6 binds EEA1 and Interacts with VPS45A, MARCH2, MARCH3 and GOPC. It is identified in a complex containing STX6, STX12, VAMP4 and VTI1A.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% glycerol, 2mM DTT
• Molecular Mass: 29.2kDa
• Protein length: 257aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMSMEDPF FVVKGEVQKA VNTAQGLFQR WTELLQDPST ATREEIDWTT NELRNNLRSI EWDLEDLDETISIVEANPRK FNLDATELSI RKAFITSTRQ VVRDMKDQMS TSSVQALAER KNRQALLGDS GSQNWSTGTT DKYGRLDREL QRANSHFIEE QQAQQQLIVE QQDEQLELVS GSIGVLKNMS QRIGGELEEQ AVMLEDFSHE LESTQSRLDN VMKKLAKVSH MTSDRRQ
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml

Gene Information

• Gene Name: STX6 syntaxin 6 [ Homo sapiens ]
• Official Symbol: STX6
• Synonyms: STX6; syntaxin 6; syntaxin-6
• Gene ID: 10228
• mRNA Refseq: NM_005819
• Protein Refseq: NP_005810
• MIM: 603944
• UniProt ID: O43752
• Chromosome Location: 1q25.3
• Pathway: Botulinum neurotoxicity, organism-specific biosystem; Disease, organism-specific biosystem; Neuronal System, organism-specific biosystem; Proteolytic cleavage of SNARE complex proteins, organism-specific biosystem; SNARE interactions in vesicular transport, organism-specific biosystem; SNARE interactions in vesicular transport, conserved biosystem
• Function: SNAP receptor activity; protein binding