Recombinant Human ATP1B1 protein, His-tagged
Cat.No. : | ATP1B1-2279H |
Product Overview : | Recombinant Human ATP1B1(63 - 303aa) fused with His tag at N-terminal was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | ATP1B1 belongs to the family of Na+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The beta subunit regulates, through assembly of alpha/beta heterodimers, the number of sodium pumps transported to the plasma membrane. The glycoprotein subunit of Na+/K+ -ATPase is encoded by multiple genes. ATP1B1 is a beta 1 subunit. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea |
Molecular Mass : | 30.4kDa (264aa) |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSEFKPTYQ DRVAPPGLTQ IPQIQKTEIS FRPNDPKSYE AYVLNIVRFL EKYKDSAQRD DMIFEDCGDVPSEPKERGDF NHERGERKVC RFKLEWLGNC SGLNDETYGY KEGKPCIIIK LNRVLGFKPK PPKNESLETY PVMKYNPNVL PVQCTGKRDEDKDKVGNVEY FGLGNSPGFP LQYYPYYGKL LQPKYLQPLL AVQFTNLTMD TEIRIECKAY GENIGYSEKD RFQGRFDVKI EVKS |
Purity : | > 90% by SDS - PAGE |
Storage : | Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 1.0 mg/ml (determined by Bradford assay) |
Gene Name : | ATP1B1 ATPase, Na+/K+ transporting, beta 1 polypeptide [ Homo sapiens ] |
Official Symbol : | ATP1B1 |
Synonyms : | ATP1B1; ATPase, Na+/K+ transporting, beta 1 polypeptide; ATP1B; sodium/potassium-transporting ATPase subunit beta-1; adenosinetriphosphatase; Na, K-ATPase beta-1 polypeptide; Beta 1-subunit of Na(+),K(+)-ATPase; sodium/potassium-dependent ATPase beta-1 subunit; sodium/potassium-transporting ATPase beta-1 chain; MGC1798; |
Gene ID : | 481 |
mRNA Refseq : | NM_001677 |
Protein Refseq : | NP_001668 |
MIM : | 182330 |
UniProt ID : | P05026 |
Chromosome Location : | 1q22-q25 |
Pathway : | Aldosterone-regulated sodium reabsorption, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, conserved biosystem; Basigin interactions, organism-specific biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Carbohydrate digestion and absorption, organism-specific biosystem; |
Function : | protein binding; sodium:potassium-exchanging ATPase activity; |
Products Types
◆ Recombinant Protein | ||
ATP1B1-71C | Recombinant Cynomolgus Monkey ATP1B1 Protein, His (Fc)-Avi-tagged | +Inquiry |
ATP1B1-17H | Active Recombinant Human ATP1B1 Protein (63-303aa), C-His tagged | +Inquiry |
ATP1B1-2550H | Recombinant Human ATP1B1 protein(101-170 aa), C-His-tagged | +Inquiry |
ATP1B1-1071H | Recombinant Human ATP1B1 protein(Glu63-Ser303), His-tagged | +Inquiry |
ATP1B1-278R | Recombinant Rhesus Macaque ATP1B1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
ATP1B1-919HCL | Recombinant Human ATP1B1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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