Recombinant Human TAF10 protein, His-tagged

• Cat.No.: TAF10-2346H
• Product Overview: Recombinant Human TAF10(84-218aa) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Description: TAF10 is one of the small subunits of TFIID that is associated with a subset of TFIID complexes. Studies with human and mammalian cells have shown that this subunit is required for transcriptional activation by the estrogen receptor, for progression through the cell cycle, and may also be required for certain cellular differentiation programs.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT
• Molecular Mass: 16.9 kDa (158aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSGAAPPEG AISNGVYVLP SAANGDVKPV VSSTPLVDFL MQLEDYTPTI PDAVTGYYLN RAGFEASDPRIIRLISLAAQ KFISDIANDA LQHCKMKGTA SGSSRSKSKD RKYTLTMEDL TPALSEYGIN VKKPHYFT
• Purity: > 85% by SDS - PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: TAF10 TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa [ Homo sapiens ]
• Official Symbol: TAF10
• Synonyms: TAF10; TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa; TAF2A, TAF2H, TATA box binding protein (TBP) associated factor, RNA polymerase II, H, 30kD; transcription initiation factor TFIID subunit 10; TAFII30; STAF28; TAFII-30; TAF(II)30; transcription initiation factor TFIID 30 kD subunit; transcription initiation factor TFIID 30 kDa subunit; TATA box binding protein (TBP)-associated factor, RNA polymerase II, H, 30kD; TAF2A; TAF2H
• Gene ID: 6881
• mRNA Refseq: NM_006284
• Protein Refseq: NP_006275
• MIM: 600475
• UniProt ID: Q12962
• Chromosome Location: 11p15.5-p15.2
• Pathway: Basal transcription factors, organism-specific biosystem; Basal transcription factors, conserved biosystem; C-MYC pathway, organism-specific biosystem; Disease, organism-specific biosystem; Gene Expression, organism-specific biosystem; HIV Infection, organism-specific biosystem; HIV Life Cycle, organism-specific biosystem
• Function: RNA polymerase binding; enzyme binding; estrogen receptor binding; contributes_to histone acetyltransferase activity; protein binding; contributes_to protein binding; contributes_to sequence-specific DNA binding transcription factor activity; transcription coactivator activity