Recombinant Human AP1AR, His-tagged

• Cat.No.: AP1AR-2321H
• Product Overview: Recombinant human AP1AR protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: Adaptor-related protein complex 1 associated regulatory protein, also known as AP1AR, is necessary for AP-1 dependent transport between the trans-Golgi network and endosomes. This protein regulates the membrane association of AP1G1/Gamma1-adaptin, one of the subunits of the AP-1 adapter complex. The direct interaction with AP1G1/Gamma1-adaptin attenuates the release of the AP-1 complex from membranes.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
• Molecular Mass: 36.4 kDa
• Protein length: 322aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGNCCWTQCF GLLRKEAGRL QRVGGGGGSK YFRTCSRGEH LTIEFENLVE SDEGESPGSS HRPLTEEEIV DLRERHYDSI AEKQKDLDKK IQKELALQEE KLRLEEEALY AAQREAARAA KQRKLLEQER QRIVQQYHPS NNGEYQSSGP EDDFESCLRN MKSQYEVFRS SRLSSDATVL TPNTESSCDL MTKTKSTSGN DDSTSLDLEW EDEEGMNRML PMRERSKTEE DILRAALKYS NKKTGSNPTS ASDDSNGLEW ENDFVSAEMD DNGNSEYSGF VNPVLELSDS GIRHSDTDQQ TR
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml

Gene Information

• Gene Name: AP1AR adaptor-related protein complex 1 associated regulatory protein [ Homo sapiens ]
• Official Symbol: AP1AR
• Synonyms: 2C18; GBAR; C4orf16; PRO0971; gamma-BAR; adaptor-related protein complex 1 associated regulatory protein; 28808; Ensembl:ENSG00000138660; AP-1 complex-associated regulatory protein;gamma-1-adaptin brefeldin A resistance protein;gamma1-adaptin brefeldin A resistance protein, gamma-BAR;adapter-related protein complex 1-associated regulatory protein
• Gene ID: 55435
• mRNA Refseq: NM_001128426.1
• Protein Refseq: NP_001121898.1
• MIM: 610851
• UniProt ID: Q63HQ0
• Chromosome Location: 4q25