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Recombinant Human CUEDC2, His-tagged

Cat.No. : CUEDC2-2299H
Product Overview : Recombinant human CUEDC2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
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  • Gene Information
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Description : CUEDC2 belongs to the CUEDC2 family and contains 1 CUE domain. This protein down-regulates ESR1 protein levels through the ubiquitination-proteasome pathway, regardless of the presence of 17 beta-estradiol. It also involves in 17 beta-estradiol-induced ESR1 degradation and controls PGR protein levels through a similar mechanism.
Source : E. coli
Species : Human
Tag : His
Form : Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT.
Molecular Mass : 34 kDa
Protein length : 310aa
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSMELERIV SAALLAFVQT HLPEADLSGL DEVIFSYVLG VLEDLGPSGP SEENFDMEAF TEMMEAYVPGFAHIPRGTIG DMMQKLSGQL SDARNKENLQ PQSSGVQGQV PISPEPLQRP EMLKEETRSS AAAAADTQDE ATGAEEELLP GVDVLLEVFP TCSVEQAQWV LAKARGDLEE AVQMLVEGKE EGPAAWEGPN QDLPRRLRGP QKDELKSFIL QKYMMVDSAE DQKIHRPMAP KEAPKKLIRYIDNQVVSTKG ERFKDVRNPE AEEMKATYIN LKPARKYRFH
Purity : >90% by SDS - PAGE
Applications : SDS-PAGE
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Concentration : 1 mg/ml
Gene Name : CUEDC2 CUE domain containing 2 [ Homo sapiens ]
Official Symbol : CUEDC2
Synonyms : C10orf66; bA18I14.5; CUE domain containing 2; 28352; Ensembl:ENSG00000107874; MGC2491; CUE domain-containing protein 2;
Gene ID : 79004
mRNA Refseq : NM_024040.2
Protein Refseq : NP_076945.2
MIM : 614142
UniProt ID : Q9H467
Chromosome Location : 10q24.32
Function : protein binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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