Recombinant human SHFM1, His-tagged


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Recombinant human SHFM1, His-tagged

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Cat.No. : SHFM1-2440H
Product Overview : Recombinant human SHFM1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Description : SHFM1, as known as 26S proteasome complex subunit DSS1, has been proposed to be a candidate gene for the autosomal dominant form of the heterogeneous limb developmental disorder split hand/split foot malformation type 1. In addition, it has been shown to directly interact with BRCA2. It also may play a role in the completion of the cell cycle.
Source : E.coli
Species : Human
Tag : His
Form : Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl
Molecular Mass : 10.7kDa (93aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
Purity : >85% by SDS - PAGE
Applications : SDS-PAGE
Storage : Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration : 1 mg/ml (determined by Bradford assay)
Gene Name : SHFM1 split hand/foot malformation (ectrodactyly) type 1 [ Homo sapiens ]
Official Symbol : SHFM1
Synonyms : SHFM1; split hand/foot malformation (ectrodactyly) type 1; SHFD1; 26S proteasome complex subunit DSS1; deleted in split hand/foot 1; DSS1; ECD; SEM1; Shfdg1; SHSF1; split hand/foot deleted protein 1; deleted in split-hand/split-foot 1; deleted in split hand/split foot protein 1; split hand/foot malformation type 1 protein;
Gene ID : 7979
mRNA Refseq : NM_006304
Protein Refseq : NP_006295
UniProt ID : P60896
Chromosome Location : 7q21.3
Pathway : Homologous recombination, organism-specific biosystem; Homologous recombination, conserved biosystem; Proteasome, organism-specific biosystem; Proteasome, conserved biosystem; Proteasome, 19S regulatory particle (PA700), organism-specific biosystem;
Function : peptidase activity; protein binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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