Recombinant human SHFM1, His-tagged SHFM1-2440H

Recombinant human SHFM1, His-tagged

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Recombinant human SHFM1, His-tagged

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Cat.No. : SHFM1-2440H
Product Overview : Recombinant human SHFM1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Description : SHFM1, as known as 26S proteasome complex subunit DSS1, has been proposed to be a candidate gene for the autosomal dominant form of the heterogeneous limb developmental disorder split hand/split foot malformation type 1. In addition, it has been shown to directly interact with BRCA2. It also may play a role in the completion of the cell cycle.
Source : E.coli
Species : Human
Tag : His
Form : Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl
Molecular Mass : 10.7kDa (93aa) confirmed by MALDI-TOF (Molecular size on SDS-PAGE will appear higher)
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSMSEKKQP VDLGLLEEDD EFEEFPAEDW AGLDEDEDAH VWEDNWDDDN VEDDFSNQLR AELEKHGYKMETS
Purity : >85% by SDS - PAGE
Applications : SDS-PAGE
Storage : Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration : 1 mg/ml (determined by Bradford assay)
Gene Name : SHFM1 split hand/foot malformation (ectrodactyly) type 1 [ Homo sapiens ]
Official Symbol : SHFM1
Synonyms : SHFM1; split hand/foot malformation (ectrodactyly) type 1; SHFD1; 26S proteasome complex subunit DSS1; deleted in split hand/foot 1; DSS1; ECD; SEM1; Shfdg1; SHSF1; split hand/foot deleted protein 1; deleted in split-hand/split-foot 1; deleted in split hand/split foot protein 1; split hand/foot malformation type 1 protein;
Gene ID : 7979
mRNA Refseq : NM_006304
Protein Refseq : NP_006295
UniProt ID : P60896
Chromosome Location : 7q21.3
Pathway : Homologous recombination, organism-specific biosystem; Homologous recombination, conserved biosystem; Proteasome, organism-specific biosystem; Proteasome, conserved biosystem; Proteasome, 19S regulatory particle (PA700), organism-specific biosystem;
Function : peptidase activity; protein binding;

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