Recombinant human FAM84B, His-tagged FAM84B-2442H

Recombinant human FAM84B, His-tagged

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Recombinant human FAM84B, His-tagged

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Cat.No. : FAM84B-2442H
Product Overview : Recombinant human FAM84B protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.
Description : FAM84B, as known as Family with sequence similarity 84, member B, coprecipitated with a downstream effector of RAS, CRAF. Binding of FAM83B with CRAF disrupted CRAF/14-3-3 interactions and increased CRAF membrane localization, resulting in elevated MAPK and mammalian target of rapamycin (mTOR) signaling. It is an oncogene and potentially represents a new target for therapeutic intervention.
Source : E.coli
Species : Human
Tag : His
Form : Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.15M NaCl,1mM DTT, 0.1mM PMSF
Molecular Mass : 36.9 kDa(333aa) confirmed by MALDI-TOF
AA Sequence : MGSSHHHHHH SSGLVPRGSH MGSMGNQVEK LTHLSYKEVP TADPTGVDRD DGPRIGVSYI FSNDDEDVEP QPPPQGPDGG GLPDGGDGPPPPQPQPYDPR LHEVECSVFY RDECIYQKSF APGSAALSTY TPENLLNKCK PGDLVEFVSQ AQYPHWAVYV GNFQVVHLHR LEVINSFLTDASQGRRGRVV NDLYRYKPLS SSAVVRNALA HVGAKERELS WRNSESFAAW CRYGKREFKI GGELRIGKQP YRLQIQLSAQ RSHTLEFQSLEDLIMEKRRN DQIGRAAVLQ ELATHLHPAE PEEGDSNVAR TTPPPGRPPA PSSEEEDGEA VAH
Purity : >85% by SDS - PAGE
Applications : SDS-PAGE
Storage : Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration : 0.5 mg/ml (determined by Bradford assay)
Gene Name : FAM84B family with sequence similarity 84, member B [ Homo sapiens ]
Official Symbol : FAM84B
Synonyms : FAM84B; family with sequence similarity 84, member B; protein FAM84B; BCMP101; breast cancer membrane associated protein 101; neurological/sensory 2; NSE2; breast cancer membrane protein 101; breast cancer membrane-associated protein 101;
Gene ID : 157638
mRNA Refseq : NM_174911
Protein Refseq : NP_777571
MIM : 609483
UniProt ID : Q96KN1
Chromosome Location : 8q24.13
Function : protein binding;

Products Types

◆ Recombinant Protein

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FAM84B-3992ZRecombinant Zebrafish FAM84B+Inquiry
FAM84B-12729HRecombinant Human FAM84B, His-tagged+Inquiry

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◆ Lysates

FAM84B-6342HCLRecombinant Human FAM84B 293 Cell Lysate+Inquiry

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Related Gene

FAM19A2FAM3CFAM129AFAM129BFAM189A2FAM200AFAM50AFAM65BFAM84AFAM84BFAM127CFAM40AFAM3BFAM3DFAM62BFAM175AFAM20CFAM164CFAM129CFAM203AFAM207AFAM188AFAM110BFAM189BFAM163AFAM206AFAM164AFAM127AFAM32AFAM35AFAM36AFAM107AFAM108A1FAM108B1FAM109AFAM109BFAM111AFAM122BFAM13BFAM13CFAM170AFAM171A1FAM173BFAM175BFAM78BFAM81BFAM101AFAM102AFAM102BFAM104BFAM178BFAM180AFAM181BFAM185AFAM188B2FAM22GFAM26DFAM26FFAM59AFAM5CFAM134BFAM135BFAM136AFAM161AFAM161BFAM19A4FAM21CFAM40BFAM83DFAM155AFAM156AFAM160B1FAM89BFAM105AFAM123BFAM124AFAM125BFAM126AFAM18B1FAM190AFAM194BFAM196AFAM46AFAM46CFAM46DFAM47AFAM47BFAM50BFAM53AFAM53BFAM53CFAM54AFAM54BFAM78AFAM82A2FAM82BFAM83EFAM83FFAM20AFAM166AFAM167AFAM168AFAM168BFAM169AFAM198BFAM111BFAM117AFAM118AFAM118BFAM120AFAM120AOSFAM120CFAM122AFAM150AFAM151AFAM153BFAM154AFAM70AFAM71AFAM71BFAM71DFAM90A1FAM91A1FAM92A1FAM92BFAM96BFAM98AFAM98BFAM174BFAM184BFAM192AFAM114A1FAM132AFAM160B2FAM172AFAM134CFAM76BFAM81AFAM131CFAM116AFAM19A3FAM76AFAM59BFAM188BFAM71F1FAM73AFAM82A1FAM83BFAM83GFAM96AFAM98CFAM110DFAM189A1FAM190BFAM214AFAM176AFAM49AFAM213AFAM204AFAM222AFAM216BFAM211AFAM212BFAM213BFAM209AFAM217BFAM176CFAM211BFAM212AFAM217AFAM221BFAM205AFAM221AFAM75E1FAM199XFAM100BFAM103A1FAM107BFAM104AFAM110CFAM115CFAM116BFAM117BFAM123AFAM125AFAM45AFAM48AFAM49BFAM123CFAM126BFAM131BFAM131AFAM134AFAM135AFAM149B1FAM13AFAM151BFAM154BFAM160A1FAM159BFAM162BFAM162AFAM166BFAM167BFAM171BFAM171A2FAM174AFAM173AFAM178AFAM179AFAM181AFAM180BFAM184AFAM186AFAM186BFAM187BFAM20BFAM19A1FAM26EFAM63AFAM57BFAM65AFAM69AFAM70BFAM71CFAM71F2FAM73BFAM105BFam108aFam115eFAM120BFAM122CFAM132BFAM133BFAM159AFAM160A2FAM163BFAM164BFAM165BFAM176BFam177aFAM177BFAM179BFAM183AFAM183BFAM193AFAM193BFAM194AFAM195AFAM195BFAM196BFAM208AFAM208BFAM210AFAM210BFAM220AFAM24AFAM25AFAM25CFAM38AFAM38BFAM55BFAM57AFAM58BFAM69BFAM69CFAM71E1FAM71E2FAM72AFAM83AFAM83CFAM89AFam92aFAM55CFAM55DFAM75D4FAM33AFAM23AFam100aFam101bFam108bFam108c1Fam110aFam114a2Fam124bFAM127BFAM133AFAM149AFam149bFam150bFAM155BFAM156BFAM157AFAM157BFam169bFam170bFAM177A1Fam18aFam18bFam18b2Fam187aFAM19A5FAM198AFAM200BFAM209BFAM21AFAM21BFAM214BFAM218AFAM219AFAM22AFAM22DFAM22FFAM222BFAM228AFAM25BFAM25GFam3aFam43aFam43bFam46bFam47cFam47eFAM48B1FAM48B2Fam5bFAM58AFam60aFam63bFAM64AFam65cFAM72BFAM72DFAM8A1Fam83hFam86aFAM86B1FAM86B2FAM86C1Fam86FAM9AFAM75A1FAM75A2FAM75A3FAM75A5FAM75A6FAM75A7FAM75C1FAM75C2FAM75D3Fam75d1aFam75d1bFam75d1cFam75d1dFam75aFAM115A

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