"SLA2" Related Products

Recombinant human SLA2, His-tagged

Cat.No.: SLA2-2474H
Product Overview: Recombinant human SLA2 protein, fused to His-tag at N-terminus, was expressed in E.coli.
Description: SLA2 is a member of the SLAP family of adapter proteins. The encoded protein may play an important receptor-proximal role in downregulating T and B cell-mediated responses and inhibits antigen receptor-induced calcium mobilization. This protein interacts with Cas-Br-M (murine) ecotropic retroviral transforming sequence c. Two transcript variants encoding distinct isoforms have been identified for this gene.
Source: E.coli
Species: Human
Tag: His
Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea
Molecular Mass: 31.0kDa (284aa)
AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMGSLPSR RKSLPSPSLS SSVQGQGPVT MEAERSKATA VALGSFPAGG PAELSLRLGE PLTIVSEDGDWWTVLSEVSG REYNIPSVHV AKVSHGWLYE GLSREKAEEL LLLPGNPGGA FLIRESQTRR GSYSLSVRLS RPASWDRIRH YRIHCLDNGW LYISPRLTFP SLQALVDHYS ELADDICCLL KEPCVLQRAG PLPGKDIPLP VTVQRTPLNW KELDSSLLFS EAATGEESLL SEGLRESLSFYISLNDEAVS LDDA
Purity: >80 % by SDS - PAGE
Applications: SDS-PAGE
Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Concentration: 0.5 mg/ml (determined by Bradford assay)
Gene Name: SLA2 Src-like-adaptor 2 [ Homo sapiens ]
Official Symbol: SLA2
Synonyms: SLA2; Src-like-adaptor 2; C20orf156; src-like-adapter 2; FLJ21992; SLAP 2; Src-like adapter protein-2; modulator of antigen receptor signaling; MARS; SLAP2; SLAP-2; MGC49845;
Gene ID: 84174
mRNA Refseq: NM_032214
Protein Refseq: NP_115590
MIM: 606577
UniProt ID: Q9H6Q3
Chromosome Location: 20q11.23
Pathway: B Cell Receptor Signaling Pathway, organism-specific biosystem; T Cell Receptor Signaling Pathway, organism-specific biosystem; TCR signaling in naive CD4+ T cells, organism-specific biosystem;
Function: SH3/SH2 adaptor activity; protein N-terminus binding; protein binding;

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