Recombinant Human ADIPOR2, GST-tagged

• Cat.No.: ADIPOR2-210H
• Product Overview: Human ADIPOR2 full-length ORF ( NP_078827.2, 1 a.a. - 386 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The adiponectin receptors, ADIPOR1 (MIM 607945) and ADIPOR2, serve as receptors for globular and full-length adiponectin (MIM 605441) and mediate increased AMPK (see MIM 602739) and PPAR-alpha (PPARA; MIM 170998) ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin.
• Source: Wheat germ
• Species: Human
• Tag: GST
• Molecular Mass: 70.3 kDa
• AA Sequence: MNEPTENRLGCSRTPEPDIRLRKGH QLDGTRRGDNDSHQGDLEPILEASV LSSHHKKSSEEHEYSDEAPQEDEGF MGMSPLLQAHHAMEKMEEFVCKVWE GRWRVIPHDVLPDWLKDNDFLLHGH RPPMPSFRACFKSIFRIHTETGNIW THLLGCVFFLCLGIFYMFRPNISFV APLQEKVVFGLFFLGAILCLSFSWL FHTVYCHSEGVSRLFSKLDYSGIAL LIMGSFVPWLYYSFYCNPQPCFIYL IVICVLGIAAIIVSQWDMFATPQYR GVRAGVFLGLGLSGIIPTLHYVISE GFLKAATIGQIGWLMLMASLYITGA ALYAARIPERFFPGKCDIWFHSHQL FHIFVVAGAFVHFHGVSNLQEFRFM IGGGCSEEDAL
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot; Antibody Production; Protein Array
• Storage: Store at -80°C. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ADIPOR2 adiponectin receptor 2 [ Homo sapiens (human) ]
• Official Symbol: ADIPOR2
• Synonyms: ADIPOR2; PAQR2; ACDCR2; adiponectin receptor 2; progestin and adipoQ receptor family member II
• Gene ID: 79602
• mRNA Refseq: NM_024551
• Protein Refseq: NP_078827
• MIM: 607946
• UniProt ID: Q86V24
• Chromosome Location: 12p13.31
• Pathway: AMPK signaling; Adipocytokine signaling pathway
• Function: hormone binding; identical protein binding; protein heterodimerization activity