Active Recombinant Human IL22 protein
Cat.No. : | IL22-461H |
Product Overview : | Recombinant Human IL22 protein(NP_065386.1)(Ala34-Ile179) was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Source : | E. coli |
Species : | Human |
Tag : | N/A |
Form : | Lyophilized from sterile PBS, pH 8.0. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bio-activity : | Measured by its ability to induce IL-10 secretion in COLO 205 human colorectal adenocarcinoma cells. The ED50 for this effect is typically 0.3-1.2 ng/mL. |
Molecular Mass : | The recombinant human IL22 consists of 147 amino acids and predicts a molecular mass of 16.9 KDa. It migrates as an approximately 15 KDa band in SDS-PAGE under reducing conditions. |
Protein Length : | Ala34-Ile179 |
Purity : | > 95 % as determined by SDS-PAGE |
Storage : | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | IL22 interleukin 22 [ Homo sapiens ] |
Official Symbol : | IL22 |
Synonyms : | IL22; interleukin 22; interleukin-22; IL 10 related T cell derived inducible factor; IL 21; IL 22; IL D110; IL TIF; ILTIF; MGC79382; MGC79384; TIFa; TIFIL 23; zcyto18; cytokine Zcyto18; IL-10-related T-cell-derived inducible factor; IL-10-related T-cell-derived-inducible factor; IL-21; IL-22; IL-TIF; IL-D110; TIFIL-23; |
Gene ID : | 50616 |
mRNA Refseq : | NM_020525 |
Protein Refseq : | NP_065386 |
MIM : | 605330 |
UniProt ID : | Q9GZX6 |
Products Types
◆ Recombinant Protein | ||
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IL22-44H | Recombinant Human IL22 Protein, C-6His tagged, Biotinylated | +Inquiry |
Il22-146M | Active Recombinant Mouse Il22 Protein | +Inquiry |
IL22-2066R | Recombinant Rhesus Macaque IL22 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
IL22-5232HCL | Recombinant Human IL22 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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Q&As (10)
Ask a questionIL22 enhances gut epithelial repair mechanisms.
IL22 activates STAT3 to modulate downstream targets.
IL22 interacts synergistically with IL-17 during inflammation.
IL22 is involved in the pathogenesis of autoimmune diseases like Crohn's.
IL22 is implicated in metabolic syndrome by affecting insulin sensitivity.
IL22 expression is upregulated in psoriasis.
IL22 expression is upregulated during viral infections like Hepatitis C.
IL22 contributes to anti-tumor immunity by activating NK cells.
IL22 promotes Th22 cell differentiation.
IL22 polymorphisms affect its binding affinity and signaling.
Customer Reviews (3)
Write a reviewHigh specificity.
Good for Th17 differentiation.
Effective in gut repair assays.
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