Recombinant Human ATG4A, His-tagged
| Cat.No. : | ATG4A-36H |
| Product Overview : | Recombinant Human Cysteine Protease ATG4A/ATG4A is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Val398) of Human ATG4A fused with a 6His tag at the N-terminus. |
- Specification
- Gene Information
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| Description : | Cysteine Protease ATG4A (ATG4A) is a cytoplasmic protein that belongs to the peptidase C54 family. ATG4A is widely expressed in many tissues at a low level, but the highest expression is observed in skeletal muscle and brain. ATG4A is a cysteine protease required for autophagy; it cleaves the C-terminal part of MAP1LC3, GABARAPL2 or GABARAP. ATG4A is inhibited by N-ethylmaleimide. It is suggested that ATG4A has a significant role in suppressing various cancers. |
| Source : | E. coli |
| Species : | Human |
| Tag : | His |
| Form : | Supplied as a 0.2 μM filtered solution of PBS, pH 7.4 |
| AA Sequence : | MGSSHHHHHHSSGLVPRGSHMESVL SKYEDQITIFTDYLEEYPDTDELVW ILGKQHLLKTEKSKL LSDISARLWFTYRRKFSPIGGTGPS SDAGWGCMLRCGQMMLAQALICRHL GRDWSWEKQKEQPKE YQRILQCFLDRKDCCYSIHQMAQMG VGEGKSIGEWFGPNTVAQVLKKLAL FDEWNSLAVYVSMDN TVVIEDIKKMCRVLPLSADTAGDRP PDSLTASNQSKGTSAYCSAWKPLLL IVPLRLGINQINPVY VDAFKECFKMPQSLGALGGKPNNAY YFIGFLGDELIFLDPHTTQTFVDTE ENGTVNDQTFHCLQS PQRMNILNLDPSVALGFFCKEEKDF DNWCSLVQKEILKENLRMFELVQKH PSHWPPFVPPAKPEV TTTGAEFIDSTEQLEEFDLEEDFEI LSV |
| Endotoxin : | Less than 0.1 ng/μg (1 IEU/μg). |
| Purity : | Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. |
| Storage : | Store at Please minimize freeze-thaw cycles. |
| Gene Name : | ATG4A ATG4 autophagy related 4 homolog A (S. cerevisiae) [ Homo sapiens ] |
| Official Symbol : | ATG4A |
| Synonyms : | ATG4A; ATG4 autophagy related 4 homolog A (S. cerevisiae); APG4 autophagy 4 homolog A (S. cerevisiae) , APG4A, AUT like 2, cysteine endopeptidase (S. cerevisiae) , AUTL2; cysteine protease ATG4A; hAPG4A; autophagin 2; autophagin-2; APG4 autophagy 4 homolog A; AUT-like 2 cysteine endopeptidase; AUT-like 2, cysteine endopeptidase; autophagy-related protein 4 homolog A; autophagy-related cysteine endopeptidase 2; APG4A; AUTL2; |
| Gene ID : | 115201 |
| mRNA Refseq : | NM_052936 |
| Protein Refseq : | NP_443168 |
| MIM : | 300663 |
| UniProt ID : | Q8WYN0 |
| Chromosome Location : | Xq22.1-q22.3 |
| Pathway : | Regulation of autophagy, organism-specific biosystem; Regulation of autophagy, conserved biosystem; |
| Function : | cysteine-type peptidase activity; peptidase activity; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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