Recombinant Human BNIP2, His-tagged
| Cat.No. : | BNIP2-45H |
| Product Overview : | Recombinant Human BCL2/Adenovirus E1B 19 kDa Protein-Interacting Protein 3/BNIP3 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Lys163) of Human BNIP3 fused with a His tag at the N-terminus. |
- Specification
- Gene Information
- Related Products
| Description : | BCL2/Adenovirus E1B 19 kDa Protein-Iinteracting Protein 3 (BNIP3) is a single-pass membrane protein. BNIP3 is a member of the NIP3 family. BNIP3 contains a single Bcl-2 homology 3 domain and interacts with the E1B 19 kDa protein. BNIP3 have been associated with pro-apoptotic function. BNIP3 is an apoptosis-inducing protein that can overcome BCL2 suppression. It plays a role in repartitioning calcium between the two major intracellular calcium stores in association with BCL2. BNIP3 involved in mitochondrial quality control via its interaction with SPATA18/MIEAP, response to mitochondrial damage, participates to mitochondrial protein catabolic process. |
| Source : | E. coli |
| Species : | Human |
| Tag : | His |
| Form : | Supplied as a 0.2 μM filtered solution of PBS, pH 7.4 |
| AA Sequence : | MNHKVHHHHHHMSQNGAPGMQEESL QGSWVELHFSNNGNGGSVPASVSIY NGDMEKILLDAQHES GRSSSKSSHCDSPPRSQTPQDTNRA SETDTHSIGEKNSSQSEEDDIERRK EVESILKKNSDWIWD WSSRPENIPPKEFLFKHPKRTATLS MRNTSVMKKGGIFSAEFLKVFLLSR PAV |
| Endotoxin : | Less than 0.1 ng/μg (1 IEU/μg). |
| Purity : | Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. |
| Storage : | Store at Please minimize freeze-thaw cycles. |
| Gene Name : | BNIP2 BCL2/adenovirus E1B 19kDa interacting protein 2 [ Homo sapiens ] |
| Official Symbol : | BNIP2 |
| Synonyms : | BNIP2; BCL2/adenovirus E1B 19kDa interacting protein 2; BCL2/adenovirus E1B 19kD interacting protein 2; BCL2/adenovirus E1B 19 kDa protein-interacting protein 2; BNIP 2; Nip2; NIP2; BNIP-2; |
| Gene ID : | 663 |
| mRNA Refseq : | NM_004330 |
| Protein Refseq : | NP_004321 |
| MIM : | 603292 |
| UniProt ID : | Q12982 |
| Chromosome Location : | 15q21.3 |
| Pathway : | CDO in myogenesis, organism-specific biosystem; Developmental Biology, organism-specific biosystem; Myogenesis, organism-specific biosystem; |
| Function : | GTPase activator activity; calcium ion binding; protein binding; |
Products Types
| ◆ Recombinant Protein | ||
| Bnip2-717M | Recombinant Mouse Bnip2 Protein, MYC/DDK-tagged | +Inquiry |
| BNIP2-293H | Recombinant Human BNIP2 Protein, GST-tagged | +Inquiry |
| BNIP2-11430Z | Recombinant Zebrafish BNIP2 | +Inquiry |
| ◆ Lysates | ||
| BNIP2-8424HCL | Recombinant Human BNIP2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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