Recombinant Human CA7

• Cat.No.: CA7-51H
• Product Overview: Recombinant Human Carbonic Anhydrase 7/CA7 is produced with our E. coli expression system. The target protein is expressed with sequence (Met1-Ala264) of Human CA7.

Specification

• Description: Carbonic Anhydrase 7 (CA7) is a member of the alpha-carbonic anhydrase family. Alpha-carbonic anhydrase is a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. Furthermore, Alpha-carbonic anhydrase is associated with many biological processes, including calcification, respiration, bone resorption, acid-base balance and the formation of aqueous humor. CA7 is activated by histamine, L-adrenaline, L- and D-histidine, and L- and D-phenylalanine, but it is inhibited coumarins, sulfonamide derivatives such as acetazolamide (AZA) by saccharin and Foscarnet.
• Source: E. coli
• Species: Human
• Form: Supplied as a 0.2 μM filtered solution of 20mM Tris-HCl, 150mM NaCl, pH 8.0
• AA Sequence: MTGHHGWGYGQDDGPSHWHKLYPIA QGDRQSPINIISSQAVYSPSLQPLE LSYEACMSLSITNNG HSVQVDFNDSDDRTVVTGGPLEGPY RLKQFHFHWGKKHDVGSEHTVDGKS FPSELHLVHWNAKKY STFGEAASAPDGLAVVGVFLETGDE HPSMNRLTDALYMVRFKGTKAQFSC FNPKCLLPASRHYWT YPGSLTTPPLSESVTWIVLREPICI SERQMGKFRSLLFTSEDDERIHMVN NFRPPQPLKGRVVKA SFRALEHHHHHH
• Endotoxin: Less than 0.1 ng/μg (1 IEU/μg).
• Purity: Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
• Storage: Store at Please minimize freeze-thaw cycles.

Gene Information

• Gene Name: CA7 carbonic anhydrase VII [ Homo sapiens ]
• Official Symbol: CA7
• Synonyms: CA7; carbonic anhydrase VII; carbonic anhydrase 7; CA-VII; carbonic dehydratase VII; carbonate dehydratase VII; CAVII
• Gene ID: 766
• mRNA Refseq: NM_001014435
• Protein Refseq: NP_001014435
• MIM: 114770
• UniProt ID: P43166
• Chromosome Location: 16q22.1
• Function: carbonate dehydratase activity; lyase activity; metal ion binding; zinc ion binding