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Recombinant Human CGREF1, His-tagged

Cat.No. : CGREF1-66H
Product Overview : Recombinant Human Cell Growth Regulator with EF Hand Domain Protein 1/CGREF1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Ala20-Ile301) of Human CGREF1 fused with a polyhistidine tag at the C-terminus.
  • Specification
  • Gene Information
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Description : Cell Growth Regulator with EF Hand Domain Protein 1 (CGREF1) is a secreted calcium ion binding protein. CGREF1 contains two EF-hand domains and both EF-hands are required for function. Human CGREF1 is synthesized as a 301 amino acid precursor that contains a 19 amino acid signal sequence, and a 282 amino acid mature chain. CGREF1 is probably digested extracellularly by an unknown serine protease generating extremely hydrophobic bioactive peptides. CGREF1 mediates cell-cell adhesion in a calcium-dependent manner. In addition, CGREF1 is able to inhibit growth in several cell lines.
Source : HEK293
Species : Human
Tag : His
AA Sequence : APKDGVTRPDSEVQHQLLPNPFQPG QEQLGLLQSYLKGLGRTEVQLEHLS REQVLLYLFALHDYD QSGQLDGLELLSMLTAALAPGAANS PTTNPVILIVDKVLETQDLNGDGLM TPAELINFPGVALRH VEPGEPLAPSPQEPQAVGRQSLLAK SPLRQETQEAPGPREEAKGQVEARR ESLDPVQEPGGQAEA DGDVPGPRGEAEGQAEAKGDAPGPR GEAGGQAEAEGDAPGPRGEAGGQAE ARENGEEAKELPGET LESKNTQNDFEVHIVQVENDEIVDH HHHHH
Endotoxin : Less than 0.1 ng/μg (1 IEU/μg).
Purity : Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
Gene Name : CGREF1 cell growth regulator with EF-hand domain 1 [ Homo sapiens ]
Official Symbol : CGREF1
Synonyms : CGREF1; cell growth regulator with EF-hand domain 1; cell growth regulator with EF hand domain protein 1; CGR11; hydrophobestin; cell growth regulatory gene 11 protein; cell growth regulator with EF hand domain 1;
Gene ID : 10669
mRNA Refseq : NM_001166239
Protein Refseq : NP_001159711
MIM : 606137
UniProt ID : Q99674
Chromosome Location : 2p23.3
Function : calcium ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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