Recombinant Human CHAD, His-tagged
Cat.No. : | CHAD-67H |
Product Overview : | Recombinant Human Chondroadherin/CHAD is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Cys23-His359) of Human CHAD fused with a polyhistidine tag at the C-terminus. |
- Specification
- Gene Information
- Related Products
Description : | Chondroadherin is a secreted protein that belongs to the small leucine-rich proteoglycan (SLRP) family of SLRP class IV subfamily. Chondroadherin contains one LRRCT domain, one LRRNT domain, and nine LRR (leucine-rich) repeats. It presents in chondrocytes at all ages. Chondroadherin is initially found as a 36-kD matrix protein isolated from bovine cartilage. It is shown to mediate chondrocyte-matrix interactions. Chondroadherin promotes attachment of chondrocytes, fibroblasts, and osteoblasts. This binding is mediated (at least for chondrocytes and fibroblasts) by the integrin α2β1. Chondroadherin may play an important role in the regulation of chondrocyte growth and proliferation. |
Source : | HEK293 |
Species : | Human |
Tag : | His |
AA Sequence : | CPQNCHCHSDLQHVICDKVGLQKIP KVSEKTKLLNLQRNNFPVLAANSFR AMPNLVSLHLQHCQI REVAAGAFRGLKQLIYLYLSHNDIR VLRAGAFDDLTELTYLYLDHNKVTE LPRGLLSPLVNLFIL QLNNNKIRELRAGAFQGAKDLRWLY LSENALSSLQPGALDDVENLAKFHV DRNQLSSYPSAALSK LRVVEELKLSHNPLKSIPDNAFQSF GRYLETLWLDNTNLEKFSDGAFLGV TTLKHVHLENNRLNQ LPSNFPFDSLETLALTNNPWKCTCQ LRGLRRWLEAKASRPDATCASPAKF KGQHIRDTDAFRSCK FPTKRSKKAGRHVDHHHHHH |
Endotoxin : | Less than 0.1 ng/μg (1 IEU/μg). |
Purity : | Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. |
Gene Name : | CHAD chondroadherin [ Homo sapiens ] |
Official Symbol : | CHAD |
Synonyms : | CHAD; chondroadherin; chondroadherin proteoglycan; SLRR4A; cartilage leucine-rich protein; |
Gene ID : | 1101 |
mRNA Refseq : | NM_001267 |
Protein Refseq : | NP_001258 |
MIM : | 602178 |
UniProt ID : | O15335 |
Chromosome Location : | 17q21.33 |
Pathway : | ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem; |
Function : | extracellular matrix structural constituent; |
Products Types
◆ Recombinant Protein | ||
CHAD-1021R | Recombinant Rat CHAD Protein, His (Fc)-Avi-tagged | +Inquiry |
CHAD-1621M | Recombinant Mouse CHAD Protein, His (Fc)-Avi-tagged | +Inquiry |
CHAD-1201H | Recombinant Human CHAD Protein, GST-Tagged | +Inquiry |
CHAD-1363R | Recombinant Rat CHAD Protein | +Inquiry |
CHAD-3363M | Recombinant Mouse CHAD Protein | +Inquiry |
◆ Lysates | ||
CHAD-182HCL | Recombinant Human CHAD lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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