||Recombinant Human 17-β-Hydroxysteroid Dehydrogenase 13/HSD17B13 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Glu20-Lys300) of Human HSD17B13 fused with a 6His tag at the C-terminus.
||17-β-Hydroxysteroid Dehydrogenase 13 (HSD17B13) is a secreted protein that belongs to the short-chain dehydrogenases/reductases (SDR) family. HSD17B13 is highly expressed in the liver, but it can also be detected in the ovary, bone marrow, kidney, brain, lung, skeletal muscle, bladder, and testis. HSD17B13 contains an ORF with a length of 900 bp, encoding a protein with a signal peptide sequence and an adh_short domain.
||ESLVKFFIPQRRKSVAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLG VTAHAYVVDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHF WITKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTS CLCPVFVNTGFTKNPSTRLWPVLETDEVVRSLIDGILTNKKMIFVPSYINIFLRLQKFLPERASA ILNRMQNIQFEAVVGHKIKMKVDHHHHHH
||Less than 0.1 ng/μg (1 IEU/μg).
||Greater than 95% as determined by reducing SDS-PAGE.