Recombinant Human MINPP1, His-tagged
Cat.No. : | MINPP1-142H |
Product Overview : | Recombinant Human Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 produced by transfected human cellss is a secreted protein with sequence (Ser31-Leu487) of Human MINPP1 fused with a polyhistidine tag at the C-terminus. |
- Specification
- Gene Information
- Related Products
Description : | Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 is an enzyme that removes 3-phosphate from inositol phosphate substrates. MINPP1 also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate. MINPP1 is synthesized as a 487 amino acid precursor that contains an 30 amino acid signal peptide and a 457 amino aicd mature chain. MINPP1 is widely expressed with the highest levels found in kidney, liver and placenta. It acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). MINPP1 may play a role in bone development (endochondral ossification). |
Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Supplied as a 0.2 μM filtered solution of 20mM Tris-HCl, 150mM NaCl, 10% Glycerol, pH 7.5 |
AA Sequence : | SLLEPRDPVASSLSPYFGTKTRYED VNPVLLSGPEAPWRDPELLEGTCTP VQLVALIRHGTRYPT VKQIRKLRQLHGLLQARGSRDGGAS STGSRDLGAALADWPLWYADWMDGQ LVEKGRQDMRQLALR LASLFPALFSRENYGRLRLITSSKH RCMDSSAAFLQGLWQHYHPGLPPPD VADMEFGPPTVNDKL MRFFDHCEKFLTEVEKNATALYHVE AFKTGPEMQNILKKVAATLQVPVND LNADLIQVAFFTCSF DLAIKGVKSPWCDVFDIDDAKVLEY LNDLKQYWKRGYGYTINSRSSCTLF QDIFQHLDKAVEQKQ RSQPISSPVILQFGHAETLLPLLSL MGYFKDKEPLTAYNYKKQMHRKFRS GLIVPYASNLIFVLY HCENAKTPKEQFRVQMLLNEKVLPL AYSQETVSFYEDLKNHYKDILQSCQ TSEECELARANSTSD ELVDHHHHHH |
Endotoxin : | Less than 0.1 ng/μg (1 IEU/μg). |
Purity : | Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. |
Storage : | Store at Please minimize freeze-thaw cycles. |
Gene Name : | MINPP1 multiple inositol-polyphosphate phosphatase 1 [ Homo sapiens ] |
Official Symbol : | MINPP1 |
Synonyms : | MINPP1; multiple inositol-polyphosphate phosphatase 1; multiple inositol polyphosphate histidine phosphatase, 1; multiple inositol polyphosphate phosphatase 1; MIPP; ins(1,3,4,5)P(4) 3-phosphatase; multiple inositol polyphosphate phosphatase 2; inositol (1,3,4,5)-tetrakisphosphate 3-phosphatase; HIPER1; MINPP2; DKFZp564L2016; |
Gene ID : | 9562 |
mRNA Refseq : | NM_001178117 |
Protein Refseq : | NP_001171588 |
MIM : | 605391 |
UniProt ID : | Q9UNW1 |
Chromosome Location : | 10q23 |
Pathway : | D-myo-inositol (1,3,4)-trisphosphate biosynthesis, organism-specific biosystem; D-myo-inositol (1,3,4)-trisphosphate biosynthesis, conserved biosystem; D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis, organism-specific biosystem; D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis, conserved biosystem; Inositol phosphate metabolism, organism-specific biosystem; Inositol phosphate metabolism, conserved biosystem; Rapoport-Luebering glycolytic shunt, organism-specific biosystem; |
Function : | acid phosphatase activity; bisphosphoglycerate 3-phosphatase activity; hydrolase activity; inositol hexakisphosphate 2-phosphatase activity; inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity; inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity; phosphohistidine phosphatase activity; |
Products Types
◆ Recombinant Protein | ||
MINPP1-1730H | Recombinant Human MINPP1 Protein (31-487 aa), His-tagged | +Inquiry |
MINPP1-1412H | Recombinant Human MINPP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
MINPP1-5344H | Recombinant Human MINPP1 Protein, GST-tagged | +Inquiry |
MINPP1-1456R | Recombinant Rat MINPP1 Protein (31-481 aa), His-tagged | +Inquiry |
Minpp1-4076M | Recombinant Mouse Minpp1 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
MINPP1-4312HCL | Recombinant Human MINPP1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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