| Description : |
Multimerin-1 (MMRN1) is a massive soluble protein found in platelets and in the endothelium of blood vessels. It contains one C1q domain, one EGF-like domain, and one EMI domain. MMRN1 is comprised of subunits linked by interchain disulfide bonds to form large, variably sized homomultimers. MMRN1 is a factor V/Va-binding protein and may function as a carrier protein for platelet factor V. Upon release following platelet activation, may limit platelet and plasma factor Va-dependent thrombin generation. MMRN1may also have functions as an extracellular matrix or adhesive protein. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
His |
| AA Sequence : |
LNNSKHSWTIPEDGNSQKTMPSASV PPNKIQSLQILPTTRVMSAEIATTP EARTSEDSLLKSTLP PSETSAPAEGVRNQTLTSTEKAEGV VKLQNLTLPTNASIKFNPGAESVVL SNSTLKFLQSFARKS NEQATSLNTVGGTGGIGGVGGTGGV GNRAPRETYLSRGDSSSSQRTDYQK SNFETTRGKNWCAYV HTRLSPTVILDNQVTYVPGGKGPCG WTGGSCPQRSQKISNPVYRMQHKIV TSLDWRCCPGYSGPK CQLRAQEQQSLIHTNQAESHTAVGR GVAEQQQQQGCGDPEVMQKMTDQVN YQAMKLTLLQKKIDN ISLTVNDVRNTYSSLEGKVSEDKSR EFQSLLKGLKSKSINVLIRDIVREQ FKIFQNDMQETVAQL FKTVSSLSEDLESTRQIIQKVNESV VSIAAQQKFVLVQENRPTLTDIVEL RNHIVNVRQEMTLTC EKPIKELEVKQTHLEGALEQEHSRS ILYYESLNKTLSKLKEVHEQLLSTE QVSDQKNAPAAESVS NNVTEYMSTLHENIKKQSLMMLQMF EDLHIQESKINNLTVSLEMEKESLR GECEDMLSKCRNDFK FQLKDTEENLHVLNQTLAEVLFPMD NKMDKMSEQLNDLTYDMEILQPLLE QGASLRQTMTYEQPK EAIVIRKKIENLTSAVNSLNFIIKE LTKRHNLLRNEVQGRDDALERRINE YALEMEDGLNKTMTI INNAIDFIQDNYALKETLSTIKDNS EIHHKCTSDMETILTFIPQFHRLND SIQTLVNDNQRYNFV LQVAKTLAGIPRDEKLNQSNFQKMY QMFNETTSQVRKYQQNMSHLEEKLL LTTKISKNFETRLQD IESKVTQTLIPYYISVKKGSVVTNE RDQALQLQVLNSRFKALEAKSIHLS INFFSLNKTLHEVLT MCHNASTSVSELNATIPKWIKHSLP DIQLLQKGLREFVEPIIQIKTQAAL SNLTCCIDRSLPGSL ANVVKSQKQVKSLPKKINALKKPTV NLTTVLIGRTQRNTDNIIYPEEYSS CSRHPCQNGGTCING RTSFTCACRHPFTGDNCTIKLVEEN ALAPDFSKGSYRYAPMVAFFASHTY GMTIPGPILFNNLDV NYGASYTPRTGKFRIPYLGVYVFKY TIESFSAHISGFLVVDGIDKLAFES ENINSEIHCDRVLTG DALLELNYGQEVWLRLAKGTIPAKF PPVTTFSGYLLYRTVDHHHHHH |
| Endotoxin : |
Less than 0.1 ng/μg (1 IEU/μg). |
| Purity : |
Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. |
