| Description : |
Low-Density Lipoprotein Receptor-Related Protein 12 (LRP12) belongs to the LDLR family. LRP12 is a type I transmembrane protein annd widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas. LRP12 contains 2 CUB domain and 5 LDL-receptor class A domain. LRP12 has been shown to interact with GNB2L1, ZFYVE9 and ITGB1BP3. LRP12 is a receptor probably, which may be involved in the internalization of lipophilic molecules and/or signal transduction. In addition, LRP12 may act as a tumor suppressor. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
His |
| Form : |
Lyophilized from a 0.2 μM filtered solution of 20mM PB, 150mM NaCl, pH 7.2 |
| AA Sequence : |
EHSENVHISGVSTACGETPEQIRAP SGIITSPGWPSEYPAKINCSWFIRA NPGEIITISFQDFDI QGSRRCNLDWLTIETYKNIESYRAC GSTIPPPYISSQDHIWIRFHSDDNI SRKGFRLAYFSGKSE EPNCACDQFRCGNGKCIPEAWKCNN MDECGDSSDEEICAKEANPPTAAAF QPCAYNQFQCLSRFT KVYTCLPESLKCDGNIDCLDLGDEI DCDVPTCGQWLKYFYGTFNSPNYPD FYPPGSNCTWLIDTG DHRKVILRFTDFKLDGTGYGDYVKI YDGLEENPHKLLRVLTAFDSHAPLT VVSSSGQIRVHFCAD KVNAARGFNATYQVDGFCLPWEIPC GGNWGCYTEQQRCDGYWHCPNGRDE TNCTMCQKEEFPCSR NGVCYPRSDRCNYQNHCPNGSDEKN CFFCQPGNFHCKNNRCVFESWVCDS QDDCGDGSDEENCPV IVDHHHHHH |
| Endotoxin : |
Less than 0.1 ng/μg (1 IEU/μg). |
| Purity : |
Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. |
| Storage : |
Lyophilized protein should be stored at Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at |
| Reconstitution : |
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in 1X PBS.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
