Active Recombinant Human MAOB

• Cat.No.: MAOB-108H
• Product Overview: A well-established source of cDNA-expressed enzymes for studies of metabolism.

Specification

• Description: MAO B is distributed at high levels in the liver, brain and platelets. Benzylamine and phenylethylamine are considered selective substrate for MAO B. Deprenyl has been shown to be a potent and selective inhibitor and is currently used in the treatment of Parkinson?s disease.
• Species: Human
• Form: 100 mM potassium phosphate (pH 7.4) for MAO assays. When evaluating new buffers it may be advisable to test new compositions relative to the buffer used for the QC assay.
• Bio-activity: Catalytic assay: Kynuramine Deamination Representative catalytic activity: 54 nmol/(min x mg protein)
• Storage: -80
• Concentration: 5 mg/ml
• Shipping: dry-ice

Gene Information

• Gene Name: MAOB monoamine oxidase B [ Homo sapiens (human) ]
• Official Symbol: MAOB
• Synonyms: MAOB; monoamine oxidase B; amine oxidase [flavin-containing] B; MAO-B; MAO, brain; MAO, platelet; tyramine oxidase; adrenalin oxidase; monoamine oxidase type B; EC 1.4.3.4
• Gene ID: 4129
• mRNA Refseq: NM_000898
• Protein Refseq: NP_000889
• MIM: 309860
• UniProt ID: P27338
• Chromosome Location: Xp11.23
• Pathway: Alpha-synuclein signaling; Amine Oxidase reactions; Arginine and proline metabolism
• Function: electron carrier activity; flavin adenine dinucleotide binding; primary amine oxidase activity